Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

Katie Morris; Edita Bulovaite; Takeshi Kaizuka; Sebastian Schnorrenberg; Candace Adams; Noboru H. Komiyama; Lorena Mendive-Tapia; Seth G. N. Grant; Mathew H. Horrocks

doi:10.1101/2023.07.13.548866

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Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace Adams, Noboru H. Komiyama, Lorena Mendive-Tapia, Seth G. N. Grant, Mathew H. Horrocks

doi: https://doi.org/10.1101/2023.07.13.548866

Katie Morris

1EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom

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Edita Bulovaite

2Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom

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Takeshi Kaizuka

2Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom

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Sebastian Schnorrenberg

3EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany

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Candace Adams

1EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom

4IRR Chemistry Hub, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, EH16 4UU, United Kingdom

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Noboru H. Komiyama

2Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom

5Simons Initiative for the Developing Brain (SIDB), Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, United Kingdom

6The Patrick Wild Centre for Research into Autism, Fragile X Syndrome & Intellectual Disabilities, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, United Kingdom

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Lorena Mendive-Tapia

4IRR Chemistry Hub, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, EH16 4UU, United Kingdom

7Centre for Inflammation Research, University of Edinburgh, Edinburgh, EH16 4UU, United Kingdom

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Seth G. N. Grant

2Genes to Cognition Program, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom

5Simons Initiative for the Developing Brain (SIDB), Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, United Kingdom

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For correspondence: [email protected] [email protected]

Mathew H. Horrocks

1EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh, EH9 3FJ, United Kingdom

4IRR Chemistry Hub, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, EH16 4UU, United Kingdom

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For correspondence: [email protected] [email protected]

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Posted July 22, 2024.

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Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace Adams, Noboru H. Komiyama, Lorena Mendive-Tapia, Seth G. N. Grant, Mathew H. Horrocks

bioRxiv 2023.07.13.548866; doi: https://doi.org/10.1101/2023.07.13.548866

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Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace Adams, Noboru H. Komiyama, Lorena Mendive-Tapia, Seth G. N. Grant, Mathew H. Horrocks

bioRxiv 2023.07.13.548866; doi: https://doi.org/10.1101/2023.07.13.548866

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