New Results
Exploring the Druggable Conformational Space of Protein Kinases Using AI-Generated Structures
View ORCID ProfileNoah B. Herrington, View ORCID ProfileDavid Stein, View ORCID ProfileYan Chak Li, View ORCID ProfileGaurav Pandey, View ORCID ProfileAvner Schlessinger
doi: https://doi.org/10.1101/2023.08.31.555779
Noah B. Herrington
aDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
David Stein
aDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
bDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
Yan Chak Li
bDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
Gaurav Pandey
bDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
cDepartment of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, New York 10029
Avner Schlessinger
aDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States
cDepartment of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, New York 10029
Article usage
Posted September 02, 2023.
Exploring the Druggable Conformational Space of Protein Kinases Using AI-Generated Structures
Noah B. Herrington, David Stein, Yan Chak Li, Gaurav Pandey, Avner Schlessinger
bioRxiv 2023.08.31.555779; doi: https://doi.org/10.1101/2023.08.31.555779
Subject Area
Subject Areas
- Biochemistry (13346)
- Bioengineering (10160)
- Bioinformatics (32494)
- Biophysics (16722)
- Cancer Biology (13801)
- Cell Biology (19627)
- Clinical Trials (138)
- Developmental Biology (10617)
- Ecology (15698)
- Epidemiology (2067)
- Evolutionary Biology (20010)
- Genetics (13210)
- Genomics (18337)
- Immunology (13435)
- Microbiology (31469)
- Molecular Biology (13110)
- Neuroscience (68622)
- Paleontology (508)
- Pathology (2124)
- Pharmacology and Toxicology (3663)
- Physiology (5711)
- Plant Biology (11753)
- Synthetic Biology (3300)
- Systems Biology (8018)
- Zoology (1812)