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Phase-separating fusion proteins drive cancer by dysregulating transcription through ectopic condensates
View ORCID ProfileNazanin Farahi, View ORCID ProfileTamas Lazar, View ORCID ProfilePeter Tompa, View ORCID ProfileBálint Mészáros, View ORCID ProfileRita Pancsa
doi: https://doi.org/10.1101/2023.09.20.558425
Nazanin Farahi
1VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie (VIB), Pleinlaan 2, 1050 Brussels, Belgium
2Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium
Tamas Lazar
1VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie (VIB), Pleinlaan 2, 1050 Brussels, Belgium
2Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium
Peter Tompa
1VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie (VIB), Pleinlaan 2, 1050 Brussels, Belgium
2Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium
3Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, 1117 Budapest, Hungary
Bálint Mészáros
4Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany
5St Jude Children’s Research Hospital, 262 Danny Thomas Place, 38105 Memphis, TN, USA
Rita Pancsa
3Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, 1117 Budapest, Hungary
Article usage
Posted November 20, 2023.
Phase-separating fusion proteins drive cancer by dysregulating transcription through ectopic condensates
Nazanin Farahi, Tamas Lazar, Peter Tompa, Bálint Mészáros, Rita Pancsa
bioRxiv 2023.09.20.558425; doi: https://doi.org/10.1101/2023.09.20.558425
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