Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures

Michael B. VanElzakker; Hannah F. Bues; Ludovica Brusaferri; Minhae Kim; Deena Saadi; Eva-Maria Ratai; Darin D. Dougherty; Marco L. Loggia

doi:10.1101/2023.10.19.563117

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Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [¹¹C]PBR28 PET correlates with vascular disease measures

View ORCID ProfileMichael B. VanElzakker, Hannah F. Bues, View ORCID ProfileLudovica Brusaferri, View ORCID ProfileMinhae Kim, Deena Saadi, View ORCID ProfileEva-Maria Ratai, View ORCID ProfileDarin D. Dougherty, View ORCID ProfileMarco L. Loggia

doi: https://doi.org/10.1101/2023.10.19.563117

Michael B. VanElzakker

1Division of Neurotherapeutics, Department of Psychiatry, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

5PolyBio Research Foundation, Medford, MA, USA

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ORCID record for Michael B. VanElzakker
For correspondence: mvanelzakker@mgh.harvard.edu

Hannah F. Bues

1Division of Neurotherapeutics, Department of Psychiatry, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Ludovica Brusaferri

2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

3Department of Computer Science And Informatics, School of Engineering, London South Bank University, London, UK

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Minhae Kim

2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Deena Saadi

1Division of Neurotherapeutics, Department of Psychiatry, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Eva-Maria Ratai

2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Darin D. Dougherty

1Division of Neurotherapeutics, Department of Psychiatry, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Marco L. Loggia

2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

4Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [¹¹C]PBR28 PET correlates with vascular disease measures

Michael B. VanElzakker, Hannah F. Bues, Ludovica Brusaferri, Minhae Kim, Deena Saadi, Eva-Maria Ratai, Darin D. Dougherty, Marco L. Loggia

bioRxiv 2023.10.19.563117; doi: https://doi.org/10.1101/2023.10.19.563117

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Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [¹¹C]PBR28 PET correlates with vascular disease measures

Michael B. VanElzakker, Hannah F. Bues, Ludovica Brusaferri, Minhae Kim, Deena Saadi, Eva-Maria Ratai, Darin D. Dougherty, Marco L. Loggia

bioRxiv 2023.10.19.563117; doi: https://doi.org/10.1101/2023.10.19.563117

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