Abstract
Through phenotypic and genetic profiling, we identified the first pan resistant Pseudomonas aeruginosa high-risk sequence type 309 (ST-309) with Guiana Extended Spectrum β-Lactamase (GES) in California, prior to a national outbreak of VIM-GES Pseudomonas aeruginosa (1). Our findings highlight detection and use of the translational murine model provide treatment implications for this emerging Pseudomonas aeruginosa.
Competing Interest Statement
The authors have declared no competing interest.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Posted November 20, 2023.
Public Health Response to Pan-Resistant Pseudomonas aeruginosa Sequence Type 309 with Tandem Guiana Extended Spectrum β-Lactamases – Genetic Characterization and In Vivo Efficacy Assessment using Translational Murine Model
