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Bridge RNAs direct modular and programmable recombination of target and donor DNA
Matthew G. Durrant, Nicholas T. Perry, James J. Pai, Aditya R. Jangid, Januka S. Athukoralage, Masahiro Hiraizumi, John P. McSpedon, April Pawluk, Hiroshi Nishimasu, Silvana Konermann, Patrick D. Hsu
doi: https://doi.org/10.1101/2024.01.24.577089
Matthew G. Durrant
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA
Nicholas T. Perry
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA
3University of California, Berkeley - University of California, San Francisco Graduate Program in Bioengineering, Berkeley, CA, USA
James J. Pai
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
Aditya R. Jangid
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA
Januka S. Athukoralage
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
Masahiro Hiraizumi
4Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
John P. McSpedon
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
April Pawluk
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
Hiroshi Nishimasu
4Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
5Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan
6Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
7Inamori Research Institute for Science, 620 Suiginya-cho, Shimogyo-ku, Kyoto 600-8411, Japan
8Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, 4-1-8, Honcho, Kawaguchi-shi, Saitama 332-0012, Japan
Silvana Konermann
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
9Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
Patrick D. Hsu
1Arc Institute, 3181 Porter Drive, Palo Alto, CA 94304, USA
2Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA
10Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA

- Supplementary Information[supplements/577089_file03.docx]
Posted January 26, 2024.
Bridge RNAs direct modular and programmable recombination of target and donor DNA
Matthew G. Durrant, Nicholas T. Perry, James J. Pai, Aditya R. Jangid, Januka S. Athukoralage, Masahiro Hiraizumi, John P. McSpedon, April Pawluk, Hiroshi Nishimasu, Silvana Konermann, Patrick D. Hsu
bioRxiv 2024.01.24.577089; doi: https://doi.org/10.1101/2024.01.24.577089
Bridge RNAs direct modular and programmable recombination of target and donor DNA
Matthew G. Durrant, Nicholas T. Perry, James J. Pai, Aditya R. Jangid, Januka S. Athukoralage, Masahiro Hiraizumi, John P. McSpedon, April Pawluk, Hiroshi Nishimasu, Silvana Konermann, Patrick D. Hsu
bioRxiv 2024.01.24.577089; doi: https://doi.org/10.1101/2024.01.24.577089
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