Abstract
The surge in genome data, with ongoing efforts aiming to sequence 1.5M eukaryotes in a decade, could revolutionise genomics, revealing the origins, evolution, and genetic innovations of biological processes. Yet, traditional genomics methods scale poorly with such large datasets. Addressing this, “FastOMA” provides linear scalability, enabling the processing of thousands of eukaryotic genomes within a day. FastOMA maintains the high accuracy and resolution of the well-established OMA approach in benchmarks. FastOMA is available at https://github.com/DessimozLab/FastOMA/.
Competing Interest Statement
The authors have declared no competing interest.
Footnotes
We added a few analyses, reported in supplementary information.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.