Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

Cody Aplin; Kara A. Zielinski; Suzette Pabit; Deborah Ogunribido; William P. Katt; Lois Pollack; Richard A. Cerione; Shawn K. Milano

doi:10.1101/2024.02.04.578794

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Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

View ORCID ProfileCody Aplin, View ORCID ProfileKara A. Zielinski, View ORCID ProfileSuzette Pabit, Deborah Ogunribido, View ORCID ProfileWilliam P. Katt, View ORCID ProfileLois Pollack, Richard A. Cerione, View ORCID ProfileShawn K. Milano

doi: https://doi.org/10.1101/2024.02.04.578794

Cody Aplin

1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853

2Department of Molecular Medicine, Cornell University, Ithaca, NY 14853

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Kara A. Zielinski

3School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853

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Suzette Pabit

3School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853

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Deborah Ogunribido

1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853

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William P. Katt

2Department of Molecular Medicine, Cornell University, Ithaca, NY 14853

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Lois Pollack

3School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853

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Richard A. Cerione

1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853

2Department of Molecular Medicine, Cornell University, Ithaca, NY 14853

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For correspondence: [email protected]

Shawn K. Milano

1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853

2Department of Molecular Medicine, Cornell University, Ithaca, NY 14853

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Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

Cody Aplin, Kara A. Zielinski, Suzette Pabit, Deborah Ogunribido, William P. Katt, Lois Pollack, Richard A. Cerione, Shawn K. Milano

bioRxiv 2024.02.04.578794; doi: https://doi.org/10.1101/2024.02.04.578794

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Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

Cody Aplin, Kara A. Zielinski, Suzette Pabit, Deborah Ogunribido, William P. Katt, Lois Pollack, Richard A. Cerione, Shawn K. Milano

bioRxiv 2024.02.04.578794; doi: https://doi.org/10.1101/2024.02.04.578794

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