Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer

Marco Barreca; Matteo Dugo; Barbara Galbardi; Balázs Győrffy; NA-PHER2 consortium; NeoTRIP consortium; Pinuccia Valagussa; Daniela Besozzi; Giuseppe Viale; Giampaolo Bianchini; Luca Gianni; Maurizio Callari

doi:10.1101/2024.02.23.581701

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Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer

Marco Barreca, Matteo Dugo, Barbara Galbardi, Balázs Győrffy, NA-PHER2 consortium, NeoTRIP consortium, Pinuccia Valagussa, Daniela Besozzi, Giuseppe Viale, Giampaolo Bianchini, Luca Gianni, Maurizio Callari

doi: https://doi.org/10.1101/2024.02.23.581701

Marco Barreca

1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

2Michelangelo Foundation, Milan, Italy

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Matteo Dugo

3IRCCS San Raffaele Hospital, Milan, Italy

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Barbara Galbardi

3IRCCS San Raffaele Hospital, Milan, Italy

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Balázs Győrffy

4Department of Bioinformatics, Semmelweis University, H-1094, Budapest, Hungary

5Department of Biophysics, Medical School, University of Pecs, H-7624, Pecs, Hungary

6Cancer Biomarker Research Group, Institute of Molecular Life Sciences, Research Centre for Natural Sciences, H-1117, Budapest, Hungary

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Pinuccia Valagussa

2Michelangelo Foundation, Milan, Italy

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Daniela Besozzi

7Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, Italy

8Bicocca Bioinformatics, Biostatistics and Bioimaging (B4) Research Centre, Milan, Italy

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Giuseppe Viale

9European Institute of Oncology, Milan, Italy

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Giampaolo Bianchini

3IRCCS San Raffaele Hospital, Milan, Italy

10UniSR San Raffaele University, Milan, Italy

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Luca Gianni

2Michelangelo Foundation, Milan, Italy

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Maurizio Callari

2Michelangelo Foundation, Milan, Italy

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For correspondence: maurizio.callari@fondazionemichelangelo.org

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Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer

bioRxiv 2024.02.23.581701; doi: https://doi.org/10.1101/2024.02.23.581701

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Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer

bioRxiv 2024.02.23.581701; doi: https://doi.org/10.1101/2024.02.23.581701

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