Thymic self-recognition-mediated TCR signal strength modulates antigen-specific CD8+ T cell pathogenicity in non-obese diabetic mice

Chia-Lo Ho; Li-Tzu Yeh; Yu-Wen Liu; Jia-Ling Dong; Huey-Kang Sytwu

doi:10.1101/2024.06.10.596762

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Thymic self-recognition-mediated TCR signal strength modulates antigen-specific CD8⁺ T cell pathogenicity in non-obese diabetic mice

Chia-Lo Ho, Li-Tzu Yeh, Yu-Wen Liu, Jia-Ling Dong, View ORCID ProfileHuey-Kang Sytwu

doi: https://doi.org/10.1101/2024.06.10.596762

Chia-Lo Ho

1Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan

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Li-Tzu Yeh

2Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan

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Yu-Wen Liu

3National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Miaoli, Taiwan

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Jia-Ling Dong

4Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan

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Huey-Kang Sytwu

1Molecular and Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan

2Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan

3National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Miaoli, Taiwan

4Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan

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ORCID record for Huey-Kang Sytwu
For correspondence: sytwu@nhri.org.tw

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Thymic self-recognition-mediated TCR signal strength modulates antigen-specific CD8⁺ T cell pathogenicity in non-obese diabetic mice

Chia-Lo Ho, Li-Tzu Yeh, Yu-Wen Liu, Jia-Ling Dong, Huey-Kang Sytwu

bioRxiv 2024.06.10.596762; doi: https://doi.org/10.1101/2024.06.10.596762

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Thymic self-recognition-mediated TCR signal strength modulates antigen-specific CD8⁺ T cell pathogenicity in non-obese diabetic mice

Chia-Lo Ho, Li-Tzu Yeh, Yu-Wen Liu, Jia-Ling Dong, Huey-Kang Sytwu

bioRxiv 2024.06.10.596762; doi: https://doi.org/10.1101/2024.06.10.596762

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