Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

Darryl A. Abbott; Ali T. Rai; Aaron Yang; Yixuan Cai; Shelcie Fabre; Austin J. Frazer; Jacob D. Deschepper; Amanda C. Poholek; Timothy W. Hand

doi:10.1101/2024.06.10.598156

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Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

View ORCID ProfileDarryl A. Abbott, Ali T. Rai, Aaron Yang, Yixuan Cai, Shelcie Fabre, Austin J. Frazer, Jacob D. Deschepper, Amanda C. Poholek, Timothy W. Hand

doi: https://doi.org/10.1101/2024.06.10.598156

Darryl A. Abbott

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA

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ORCID record for Darryl A. Abbott

Ali T. Rai

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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Aaron Yang

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA

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Yixuan Cai

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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Shelcie Fabre

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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Austin J. Frazer

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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Jacob D. Deschepper

4University of Pittsburgh Gnotobiotic Core Facility, University of Pittsburgh School of Medicine, Pittsburgh PA

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Amanda C. Poholek

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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Timothy W. Hand

1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh PA

2Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh PA

3UPMC Children’s Hospital of Pittsburgh, Pittsburgh PA

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For correspondence: handt@pitt.edu

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Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

Darryl A. Abbott, Ali T. Rai, Aaron Yang, Yixuan Cai, Shelcie Fabre, Austin J. Frazer, Jacob D. Deschepper, Amanda C. Poholek, Timothy W. Hand

bioRxiv 2024.06.10.598156; doi: https://doi.org/10.1101/2024.06.10.598156

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Maternal Immunoglobulin A regulates the development of the neonatal microbiota and intestinal microbiota-specific CD4+ T cell responses

Darryl A. Abbott, Ali T. Rai, Aaron Yang, Yixuan Cai, Shelcie Fabre, Austin J. Frazer, Jacob D. Deschepper, Amanda C. Poholek, Timothy W. Hand

bioRxiv 2024.06.10.598156; doi: https://doi.org/10.1101/2024.06.10.598156

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