Lineage-specific CDK activity dynamics characterize early mammalian development

Bechara Saykali; Andy D. Tran; James A. Cornwell; Matthew A. Caldwell; Paniz Rezvan Sangsari; Nicole Y. Morgan; Michael J. Kruhlak; Steven D. Cappell; Sergio Ruiz

doi:10.1101/2024.06.14.599098

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Lineage-specific CDK activity dynamics characterize early mammalian development

Bechara Saykali, Andy D. Tran, James A. Cornwell, Matthew A. Caldwell, Paniz Rezvan Sangsari, Nicole Y. Morgan, Michael J. Kruhlak, Steven D. Cappell, Sergio Ruiz

doi: https://doi.org/10.1101/2024.06.14.599098

Bechara Saykali

1Laboratory of Genome Integrity, CCR, NCI, NIH, Bethesda, MD, USA

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Andy D. Tran

2Laboratory of Cancer Biology and Genetics, CCR, NCI, National Institutes of Health, Bethesda, MD, USA

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James A. Cornwell

2Laboratory of Cancer Biology and Genetics, CCR, NCI, National Institutes of Health, Bethesda, MD, USA

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Matthew A. Caldwell

1Laboratory of Genome Integrity, CCR, NCI, NIH, Bethesda, MD, USA

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Paniz Rezvan Sangsari

3Biomedical Engineering and Physical Science Shared Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA

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Nicole Y. Morgan

3Biomedical Engineering and Physical Science Shared Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA

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Michael J. Kruhlak

2Laboratory of Cancer Biology and Genetics, CCR, NCI, National Institutes of Health, Bethesda, MD, USA

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Steven D. Cappell

2Laboratory of Cancer Biology and Genetics, CCR, NCI, National Institutes of Health, Bethesda, MD, USA

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Sergio Ruiz

1Laboratory of Genome Integrity, CCR, NCI, NIH, Bethesda, MD, USA

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For correspondence: [email protected]

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Lineage-specific CDK activity dynamics characterize early mammalian development

Bechara Saykali, Andy D. Tran, James A. Cornwell, Matthew A. Caldwell, Paniz Rezvan Sangsari, Nicole Y. Morgan, Michael J. Kruhlak, Steven D. Cappell, Sergio Ruiz

bioRxiv 2024.06.14.599098; doi: https://doi.org/10.1101/2024.06.14.599098

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Lineage-specific CDK activity dynamics characterize early mammalian development

Bechara Saykali, Andy D. Tran, James A. Cornwell, Matthew A. Caldwell, Paniz Rezvan Sangsari, Nicole Y. Morgan, Michael J. Kruhlak, Steven D. Cappell, Sergio Ruiz

bioRxiv 2024.06.14.599098; doi: https://doi.org/10.1101/2024.06.14.599098

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