An INS-1 β-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

Nina Stremmel; Oliver Lemke; Kathrin Textoris-Taube; Daniela Ludwig; Michael Mülleder; Julia Muenzner; Markus Ralser

doi:10.1101/2024.07.12.603204

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An INS-1 β-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

View ORCID ProfileNina Stremmel, View ORCID ProfileOliver Lemke, Kathrin Textoris-Taube, Daniela Ludwig, Michael Mülleder, View ORCID ProfileJulia Muenzner, View ORCID ProfileMarkus Ralser

doi: https://doi.org/10.1101/2024.07.12.603204

Nina Stremmel

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Oliver Lemke

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Kathrin Textoris-Taube

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

2Core Facility High-Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Daniela Ludwig

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

2Core Facility High-Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Michael Mülleder

2Core Facility High-Throughput Mass Spectrometry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Julia Muenzner

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

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Markus Ralser

1Institute of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany

3The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

4Max Planck Institute for Molecular Genetics, Berlin, Germany

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For correspondence: markus.ralser@charite.de

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An INS-1 β-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

Nina Stremmel, Oliver Lemke, Kathrin Textoris-Taube, Daniela Ludwig, Michael Mülleder, Julia Muenzner, Markus Ralser

bioRxiv 2024.07.12.603204; doi: https://doi.org/10.1101/2024.07.12.603204

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An INS-1 β-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

Nina Stremmel, Oliver Lemke, Kathrin Textoris-Taube, Daniela Ludwig, Michael Mülleder, Julia Muenzner, Markus Ralser

bioRxiv 2024.07.12.603204; doi: https://doi.org/10.1101/2024.07.12.603204

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