New Results
Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition
A. Kamesh, C.A. Kadgien, N. Kuhlmann, S. Coady, E.P. Hurley, J.C. Barron, M.P. Parsons, A.J. Milnerwood
doi: https://doi.org/10.1101/2024.09.30.615858
A. Kamesh
1The Neuro, McGill University, Montreal, Canada
C.A. Kadgien
1The Neuro, McGill University, Montreal, Canada
2Centre for Applied Neurogenetics, University of British Columbia, Vancouver, Canada
N. Kuhlmann
1The Neuro, McGill University, Montreal, Canada
2Centre for Applied Neurogenetics, University of British Columbia, Vancouver, Canada
S. Coady
1The Neuro, McGill University, Montreal, Canada
E.P. Hurley
3Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John’s, Canada
J.C. Barron
3Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John’s, Canada
M.P. Parsons
3Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John’s, Canada
A.J. Milnerwood
1The Neuro, McGill University, Montreal, Canada
2Centre for Applied Neurogenetics, University of British Columbia, Vancouver, Canada
Posted October 01, 2024.
Emergent glutamate & dopamine dysfunction in VPS35(D620N) knock-in mice and rapid reversal by LRRK2 inhibition
A. Kamesh, C.A. Kadgien, N. Kuhlmann, S. Coady, E.P. Hurley, J.C. Barron, M.P. Parsons, A.J. Milnerwood
bioRxiv 2024.09.30.615858; doi: https://doi.org/10.1101/2024.09.30.615858
Subject Area
Subject Areas
- Biochemistry (13150)
- Bioengineering (9977)
- Bioinformatics (31989)
- Biophysics (16505)
- Cancer Biology (13574)
- Cell Biology (19290)
- Clinical Trials (138)
- Developmental Biology (10444)
- Ecology (15494)
- Epidemiology (2067)
- Evolutionary Biology (19776)
- Genetics (13090)
- Genomics (18122)
- Immunology (13232)
- Microbiology (30973)
- Molecular Biology (12901)
- Neuroscience (67633)
- Paleontology (495)
- Pathology (2083)
- Pharmacology and Toxicology (3601)
- Physiology (5624)
- Plant Biology (11602)
- Synthetic Biology (3234)
- Systems Biology (7917)
- Zoology (1792)