Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Yanli Wu; Heng Zhang; Jiuyin Xu; Kai Wu; Wen Hu; Canrong Wu; H. Eric Xu

doi:10.1101/2024.10.10.617574

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Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Yanli Wu, Heng Zhang, Jiuyin Xu, Kai Wu, Wen Hu, Canrong Wu, View ORCID ProfileH. Eric Xu

doi: https://doi.org/10.1101/2024.10.10.617574

Yanli Wu

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

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Heng Zhang

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

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Jiuyin Xu

2School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China

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Kai Wu

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

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Wen Hu

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

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Canrong Wu

3Translational Center for Structural Biology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

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For correspondence: eric.xu@simm.ac.cn wcr13215@rjh.com.cn

H. Eric Xu

1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

3Translational Center for Structural Biology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

4University of Chinese Academy of Sciences, Beijing 100049, China

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ORCID record for H. Eric Xu
For correspondence: eric.xu@simm.ac.cn wcr13215@rjh.com.cn

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Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Yanli Wu, Heng Zhang, Jiuyin Xu, Kai Wu, Wen Hu, Canrong Wu, H. Eric Xu

bioRxiv 2024.10.10.617574; doi: https://doi.org/10.1101/2024.10.10.617574

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Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Yanli Wu, Heng Zhang, Jiuyin Xu, Kai Wu, Wen Hu, Canrong Wu, H. Eric Xu

bioRxiv 2024.10.10.617574; doi: https://doi.org/10.1101/2024.10.10.617574

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