Abstract
There is a growing demand for sophisticated behavioral analysis systems that minimize bias in multi-animal and semi-natural environments. We present “IntelliProfiler,” an advanced system using radio frequency identification (RFID) technology to enable fully automated behavior analyses of multiple mice within a home cage. IntelliProfiler continuously monitors up to 16 mice, capturing both locomotor activity and social dynamics over extended periods. Our findings revealed that male mice maintain broader social distances than females, with group size playing a key role in shaping male social network dynamics. Furthermore, aging in males significantly impacts both locomotor activity and social interaction in a group size-dependent manner. With its ability to provide in-depth analysis of individual and group behaviors, IntelliProfiler offers a novel approach for exploring complex social interactions and group dynamics, advancing the field of behavioral science.
Competing Interest Statement
The authors have declared no competing interest.
