Article Information
History
- October 28, 2024.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Caroline M. Wilson1,2,3,4,
- Greg C. Pommier2,3,5,
- Daniel D. Richman6,
- Nicholas Sambold4,
- Jeffrey A. Hussmann7,8,9,
- Jonathan S. Weissman8,9,10,11 and
- Luke A. Gilbert2,3,4,*,12
- 1Tetrad Graduate Program, University of California, San Francisco, CA 94158, USA
- 2Department of Urology, University of California, San Francisco, CA 94158, USA
- 3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
- 4Arc Institute, Palo Alto, CA 94304, USA
- 5Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
- 6Department of Computer Science, Stanford University, Stanford, CA 94305, USA
- 7Prime Medicine, Cambridge, MA 02142, USA
- 8Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
- 9Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA
- 10David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
- 11Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
- ↵*Correspondence: luke.gilbert{at}ucsf.edu or luke{at}arcinstitute.org (L.A.G.)
Posted October 28, 2024.
Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
