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Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
View ORCID ProfileCaroline M. Wilson, Greg C. Pommier, Daniel D. Richman, Nicholas Sambold, Jeffrey A. Hussmann, Jonathan S. Weissman, View ORCID ProfileLuke A. Gilbert
doi: https://doi.org/10.1101/2024.10.28.620517
Caroline M. Wilson
1Tetrad Graduate Program, University of California, San Francisco, CA 94158, USA
2Department of Urology, University of California, San Francisco, CA 94158, USA
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
4Arc Institute, Palo Alto, CA 94304, USA
Greg C. Pommier
2Department of Urology, University of California, San Francisco, CA 94158, USA
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
5Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Daniel D. Richman
6Department of Computer Science, Stanford University, Stanford, CA 94305, USA
Nicholas Sambold
4Arc Institute, Palo Alto, CA 94304, USA
Jeffrey A. Hussmann
7Prime Medicine, Cambridge, MA 02142, USA
8Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
9Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA
Jonathan S. Weissman
8Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
9Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA
10David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
11Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Luke A. Gilbert
2Department of Urology, University of California, San Francisco, CA 94158, USA
3Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
4Arc Institute, Palo Alto, CA 94304, USA
Article usage
Posted October 28, 2024.
Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
Caroline M. Wilson, Greg C. Pommier, Daniel D. Richman, Nicholas Sambold, Jeffrey A. Hussmann, Jonathan S. Weissman, Luke A. Gilbert
bioRxiv 2024.10.28.620517; doi: https://doi.org/10.1101/2024.10.28.620517
Combinatorial effector targeting (COMET) for transcriptional modulation and locus-specific biochemistry
Caroline M. Wilson, Greg C. Pommier, Daniel D. Richman, Nicholas Sambold, Jeffrey A. Hussmann, Jonathan S. Weissman, Luke A. Gilbert
bioRxiv 2024.10.28.620517; doi: https://doi.org/10.1101/2024.10.28.620517
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