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4-Methylpyrazole-mediated inhibition of Cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity
Jephte Y. Akakpo, Erika Abbott, Benjamin L. Woolbright, Anup Ramachandran, Rick G. Schnellmann, Darren P. Wallace, John A. Taylor
doi: https://doi.org/10.1101/2024.11.10.622845
Jephte Y. Akakpo
1Department of Pharmacology, Toxicology & Thzerapeutics,
Erika Abbott
5Department of Urology, University of Kansas Medical Center, Kansas City, KS
Benjamin L. Woolbright
2Department of Cancer Biology,
Anup Ramachandran
1Department of Pharmacology, Toxicology & Thzerapeutics,
Rick G. Schnellmann
3Department of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona, USA; Coit Center for Longevity and Neurotherapeutics, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona, USA; BIO5 Institute, College of Medicine, University of Arizona, Tucson, Arizona, USA
Darren P. Wallace
4Department of Internal Medicine and the Jared Grantham Kidney Institute,
John A. Taylor
2Department of Cancer Biology,
5Department of Urology, University of Kansas Medical Center, Kansas City, KS

Article usage
Posted January 08, 2025.
4-Methylpyrazole-mediated inhibition of Cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity
Jephte Y. Akakpo, Erika Abbott, Benjamin L. Woolbright, Anup Ramachandran, Rick G. Schnellmann, Darren P. Wallace, John A. Taylor
bioRxiv 2024.11.10.622845; doi: https://doi.org/10.1101/2024.11.10.622845
4-Methylpyrazole-mediated inhibition of Cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity
Jephte Y. Akakpo, Erika Abbott, Benjamin L. Woolbright, Anup Ramachandran, Rick G. Schnellmann, Darren P. Wallace, John A. Taylor
bioRxiv 2024.11.10.622845; doi: https://doi.org/10.1101/2024.11.10.622845
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