Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models

Chenxu Lei; Bocheng Zhang; Junji Yamaguchi; Risako Tamura; Xingyu Cao; Yunhui Liu; Masahide Seki; Yutaka Suzuki; Kuninori Suzuki; Isei Tanida; Yasuo Uchiyama; Tatsuhiro Hisatsune

doi:10.1101/2024.11.12.622892

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Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models

Chenxu Lei, Bocheng Zhang, Junji Yamaguchi, Risako Tamura, Xingyu Cao, Yunhui Liu, Masahide Seki, Yutaka Suzuki, Kuninori Suzuki, View ORCID ProfileIsei Tanida, Yasuo Uchiyama, Tatsuhiro Hisatsune

doi: https://doi.org/10.1101/2024.11.12.622892

Chenxu Lei

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Bocheng Zhang

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Junji Yamaguchi

2Laboratory of Morphology and Image Analysis, Biomedical Research Core Facilities, Juntendo University Graduate School of Medicine, Tokyo, Japan

3Department of Cellular and Molecular Neuropathology, Juntendo University Graduate School of Medicine, Tokyo, Japan

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Risako Tamura

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Xingyu Cao

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Yunhui Liu

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Masahide Seki

4Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Yutaka Suzuki

4Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

5Life Science Data Research Center, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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Kuninori Suzuki

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

6Collaborative Research Institute for Innovative Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

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Isei Tanida

3Department of Cellular and Molecular Neuropathology, Juntendo University Graduate School of Medicine, Tokyo, Japan

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ORCID record for Isei Tanida

Yasuo Uchiyama

3Department of Cellular and Molecular Neuropathology, Juntendo University Graduate School of Medicine, Tokyo, Japan

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Tatsuhiro Hisatsune

1Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

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For correspondence: [email protected]

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Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models

Chenxu Lei, Bocheng Zhang, Junji Yamaguchi, Risako Tamura, Xingyu Cao, Yunhui Liu, Masahide Seki, Yutaka Suzuki, Kuninori Suzuki, Isei Tanida, Yasuo Uchiyama, Tatsuhiro Hisatsune

bioRxiv 2024.11.12.622892; doi: https://doi.org/10.1101/2024.11.12.622892

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Impact of astrocytic C3-production on neuronal mitochondrial dysfunction in tauopathy mouse models

Chenxu Lei, Bocheng Zhang, Junji Yamaguchi, Risako Tamura, Xingyu Cao, Yunhui Liu, Masahide Seki, Yutaka Suzuki, Kuninori Suzuki, Isei Tanida, Yasuo Uchiyama, Tatsuhiro Hisatsune

bioRxiv 2024.11.12.622892; doi: https://doi.org/10.1101/2024.11.12.622892

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