Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation

Riku Kawanabe-Kobayashi; Sawako Uchiyama; Kohei Yoshihara; Daiki Kojima; Thomas McHugh; Izuho Hatada; Ko Matsui; Kenji F. Tanaka; Makoto Tsuda

doi:10.1101/2024.11.14.623627

New Results

Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation

Riku Kawanabe-Kobayashi, Sawako Uchiyama, Kohei Yoshihara, Daiki Kojima, View ORCID ProfileThomas McHugh, Izuho Hatada, Ko Matsui, View ORCID ProfileKenji F. Tanaka, View ORCID ProfileMakoto Tsuda

doi: https://doi.org/10.1101/2024.11.14.623627

Riku Kawanabe-Kobayashi

1Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sawako Uchiyama

1Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kohei Yoshihara

1Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Daiki Kojima

1Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Thomas McHugh

2Laboratory for Circuit and Behavioral Physiology, RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Thomas McHugh

Izuho Hatada

3Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8512, Japan

4Viral Vector Core, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ko Matsui

5Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kenji F. Tanaka

6Division of Brain Sciences, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kenji F. Tanaka

Makoto Tsuda

1Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

7Kyushu University Institute for Advanced Study, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Makoto Tsuda
For correspondence: [email protected]

Abstract
Full Text
Info/History
Metrics
Preview PDF

Article usage

Article usage: November 2024 to March 2025

	Abstract	Full	Pdf
Nov 2024	268	32	170
Dec 2024	88	31	42
Jan 2025	85	29	31
Feb 2025	41	16	16
Mar 2025	22	5	11

View the discussion thread.

PreviousNext

Posted November 14, 2024.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation

Riku Kawanabe-Kobayashi, Sawako Uchiyama, Kohei Yoshihara, Daiki Kojima, Thomas McHugh, Izuho Hatada, Ko Matsui, Kenji F. Tanaka, Makoto Tsuda

bioRxiv 2024.11.14.623627; doi: https://doi.org/10.1101/2024.11.14.623627

Share This Article:

Citation Tools

Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced pain facilitation

Riku Kawanabe-Kobayashi, Sawako Uchiyama, Kohei Yoshihara, Daiki Kojima, Thomas McHugh, Izuho Hatada, Ko Matsui, Kenji F. Tanaka, Makoto Tsuda

bioRxiv 2024.11.14.623627; doi: https://doi.org/10.1101/2024.11.14.623627

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Neuroscience

Subject Areas

All Articles

Animal Behavior and Cognition (6204)
Biochemistry
Biochemistry (14152)
Bioengineering (10820)
Bioinformatics (34299)
Biophysics (17643)
Cancer Biology (14745)
Cell Biology (20767)
Clinical Trials (138)
Developmental Biology (11174)
Ecology (16496)
Epidemiology (2067)
Evolutionary Biology (20807)
Genetics (13669)
Genomics (19086)
Immunology (14235)
Microbiology (33112)
Molecular Biology (13819)
Neuroscience (72361)
Paleontology (542)
Pathology (2278)
Pharmacology and Toxicology (3858)
Physiology (6100)
Plant Biology (12387)
Scientific Communication and Education (1839)
Synthetic Biology (3455)
Systems Biology (8369)
Zoology (1913)