Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights

Jingyou Rao; Mingsen Wang; Matthew K Howard; Christian Macdonald; James S. Fraser; Willow Coyote-Maestas; Harold Pimentel

doi:10.1101/2025.01.09.632281

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Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights

View ORCID ProfileJingyou Rao, View ORCID ProfileMingsen Wang, View ORCID ProfileMatthew K Howard, View ORCID ProfileChristian Macdonald, View ORCID ProfileJames S. Fraser, View ORCID ProfileWillow Coyote-Maestas, View ORCID ProfileHarold Pimentel

doi: https://doi.org/10.1101/2025.01.09.632281

Jingyou Rao

1Department of Computer Science, UCLA, CA, United States

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For correspondence: [email protected]

Mingsen Wang

2Department of Mathematics, Baruch College CUNY, NY, United States

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Matthew K Howard

3Department of Bioengineering and Therapeutic Sciences, UCSF, CA, United States

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Christian Macdonald

4Tetrad Graduate Program, UCSF, CA, United States

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James S. Fraser

5Department of Pharmaceutical Chemistry, UCSF, CA, United States

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Willow Coyote-Maestas

6Quantitative Biosciences Institute, UCSF, CA, United States

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Harold Pimentel

7Department of Computational Medicine, David Geffen School of Medicine, UCLA, CA, United States

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Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights

Jingyou Rao, Mingsen Wang, Matthew K Howard, Christian Macdonald, James S. Fraser, Willow Coyote-Maestas, Harold Pimentel

bioRxiv 2025.01.09.632281; doi: https://doi.org/10.1101/2025.01.09.632281

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Rosace-AA: Enhancing Interpretation of Deep Mutational Scanning Data with Amino Acid Substitution and Position-Specific Insights

Jingyou Rao, Mingsen Wang, Matthew K Howard, Christian Macdonald, James S. Fraser, Willow Coyote-Maestas, Harold Pimentel

bioRxiv 2025.01.09.632281; doi: https://doi.org/10.1101/2025.01.09.632281

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