Generative modeling for RNA splicing predictions and design

Di Wu; Natalie Maus; Anupama Jha; Kevin Yang; Benjamin D. Wales-McGrath; San Jewell; Anna Tangiyan; Peter Choi; Jacob R. Gardner; Yoseph Barash

doi:10.1101/2025.01.20.633986

New Results

Generative modeling for RNA splicing predictions and design

Di Wu, Natalie Maus, View ORCID ProfileAnupama Jha, Kevin Yang, Benjamin D. Wales-McGrath, San Jewell, Anna Tangiyan, View ORCID ProfilePeter Choi, Jacob R. Gardner, View ORCID ProfileYoseph Barash

doi: https://doi.org/10.1101/2025.01.20.633986

Di Wu

1Department of Computer and Information Science, School of Engineering, University of Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Natalie Maus

1Department of Computer and Information Science, School of Engineering, University of Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Anupama Jha

2Department of Genome Sciences, University of Washington;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Anupama Jha

Kevin Yang

3Department of Genetics, Perelman School of Medicine, University of Pennsylvania;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Benjamin D. Wales-McGrath

3Department of Genetics, Perelman School of Medicine, University of Pennsylvania;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

San Jewell

3Department of Genetics, Perelman School of Medicine, University of Pennsylvania;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Anna Tangiyan

5Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Peter Choi

4Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania

5Division of Cancer Pathobiology, The Children’s Hospital of Philadelphia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Peter Choi

Jacob R. Gardner

1Department of Computer and Information Science, School of Engineering, University of Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yoseph Barash

1Department of Computer and Information Science, School of Engineering, University of Pennsylvania

3Department of Genetics, Perelman School of Medicine, University of Pennsylvania;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Yoseph Barash
For correspondence: [email protected]

Abstract
Full Text
Info/History
Metrics
Preview PDF

Article usage

Article usage: January 2025 to March 2025

	Abstract	Full	Pdf
Jan 2025	537	23	173
Feb 2025	256	73	216
Mar 2025	49	21	51

View the discussion thread.

PreviousNext

Posted January 24, 2025.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Generative modeling for RNA splicing predictions and design

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Generative modeling for RNA splicing predictions and design

Di Wu, Natalie Maus, Anupama Jha, Kevin Yang, Benjamin D. Wales-McGrath, San Jewell, Anna Tangiyan, Peter Choi, Jacob R. Gardner, Yoseph Barash

bioRxiv 2025.01.20.633986; doi: https://doi.org/10.1101/2025.01.20.633986

Share This Article:

Citation Tools

Generative modeling for RNA splicing predictions and design

Di Wu, Natalie Maus, Anupama Jha, Kevin Yang, Benjamin D. Wales-McGrath, San Jewell, Anna Tangiyan, Peter Choi, Jacob R. Gardner, Yoseph Barash

bioRxiv 2025.01.20.633986; doi: https://doi.org/10.1101/2025.01.20.633986

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Bioinformatics

Subject Areas

All Articles

Animal Behavior and Cognition (6209)
Biochemistry
Biochemistry (14164)
Bioengineering (10825)
Bioinformatics (34310)
Biophysics (17648)
Cancer Biology (14751)
Cell Biology (20780)
Clinical Trials (138)
Developmental Biology (11178)
Ecology (16501)
Epidemiology (2067)
Evolutionary Biology (20808)
Genetics (13675)
Genomics (19092)
Immunology (14242)
Microbiology (33131)
Molecular Biology (13823)
Neuroscience (72393)
Paleontology (542)
Pathology (2278)
Pharmacology and Toxicology (3860)
Physiology (6101)
Plant Biology (12388)
Scientific Communication and Education (1839)
Synthetic Biology (3457)
Systems Biology (8369)
Zoology (1913)