Article Information
History
- February 4, 2025.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Sofía Castelli1,2,
- Wesley V. Wilson1,2,
- Ugur Uslu1,2,
- Amanda Finck1,2,
- Charles-Antoine Assenmacher3,
- Sebastian J. Atoche1,2,
- Mikko Siurala1,2,
- Regina M. Young1,2,#,* and
- Carl H. June1,2,#,**
- 1Center for Cellular Immunotherapies, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA
- 2Parker Institute for Cancer Immunotherapy at University of Pennsylvania, Philadelphia, PA, 19104, USA
- 3Comparative Pathology Core, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA
↵# These authors contributed equally to this work
Posted February 04, 2025.
IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing anti-tumor efficacy
