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Deficiency of nucleotide excision repair explains mutational signature observed in cancer
Myrthe Jager, Francis Blokzijl, Ewart Kuijk, Johanna Bertl, Maria Vougioukalaki, Roel Janssen, Nicolle Besselink, Sander Boymans, Joep de Ligt, Jakob Skou Pedersen, Jan Hoeijmakers, Joris Pothof, Ruben van Boxtel, Edwin Cuppen
doi: https://doi.org/10.1101/221168
Myrthe Jager
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Francis Blokzijl
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Ewart Kuijk
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Johanna Bertl
2Department of Molecular Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark
Maria Vougioukalaki
3Erasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands
Roel Janssen
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Nicolle Besselink
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Sander Boymans
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Joep de Ligt
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Jakob Skou Pedersen
2Department of Molecular Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark
Jan Hoeijmakers
3Erasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands
Joris Pothof
3Erasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands
Ruben van Boxtel
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Edwin Cuppen
1Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands
Posted November 15, 2018.
Deficiency of nucleotide excision repair explains mutational signature observed in cancer
Myrthe Jager, Francis Blokzijl, Ewart Kuijk, Johanna Bertl, Maria Vougioukalaki, Roel Janssen, Nicolle Besselink, Sander Boymans, Joep de Ligt, Jakob Skou Pedersen, Jan Hoeijmakers, Joris Pothof, Ruben van Boxtel, Edwin Cuppen
bioRxiv 221168; doi: https://doi.org/10.1101/221168
Deficiency of nucleotide excision repair explains mutational signature observed in cancer
Myrthe Jager, Francis Blokzijl, Ewart Kuijk, Johanna Bertl, Maria Vougioukalaki, Roel Janssen, Nicolle Besselink, Sander Boymans, Joep de Ligt, Jakob Skou Pedersen, Jan Hoeijmakers, Joris Pothof, Ruben van Boxtel, Edwin Cuppen
bioRxiv 221168; doi: https://doi.org/10.1101/221168
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