New Results
Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes
Anika Gupta, Heiko Horn, Parisa Razaz, April Kim, Michael Lawrence, Gad Getz, Kasper Lage
doi: https://doi.org/10.1101/222687
Anika Gupta
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
2Departments of Biology and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Heiko Horn
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
3Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Parisa Razaz
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
4Center for Genomic Medicine and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
April Kim
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Michael Lawrence
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
5Department of Pathology and MGH Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA
Gad Getz
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
5Department of Pathology and MGH Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA
Kasper Lage
1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
3Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Article usage
Posted November 21, 2017.
Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes
Anika Gupta, Heiko Horn, Parisa Razaz, April Kim, Michael Lawrence, Gad Getz, Kasper Lage
bioRxiv 222687; doi: https://doi.org/10.1101/222687
Subject Area
Subject Areas
- Biochemistry (11715)
- Bioengineering (8723)
- Bioinformatics (29129)
- Biophysics (14936)
- Cancer Biology (12049)
- Cell Biology (17359)
- Clinical Trials (138)
- Developmental Biology (9406)
- Ecology (14144)
- Epidemiology (2067)
- Evolutionary Biology (18268)
- Genetics (12221)
- Genomics (16767)
- Immunology (11843)
- Microbiology (28014)
- Molecular Biology (11560)
- Neuroscience (60814)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3231)
- Physiology (4940)
- Plant Biology (10384)
- Synthetic Biology (2878)
- Systems Biology (7333)
- Zoology (1642)