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Combination of mitochondrial tRNA and OXPHOS mutation reduces lifespan and physical condition in aged mice
G. Reichart, J. Mayer, T. Tokay, F. Lange, C. Johne, S. Baltrusch, M. Tiedge, G. Fuellen, S. Ibrahim, R. Köhling
doi: https://doi.org/10.1101/233593
G. Reichart
1Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Gertrudenstraße 9, 18057 Rostock, Germany
J. Mayer
1Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Gertrudenstraße 9, 18057 Rostock, Germany
T. Tokay
1Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Gertrudenstraße 9, 18057 Rostock, Germany
6Center for Life Sciences, Nazarbayev University, 53 Kabanbay batyr ave., Astana 010000, Republic of Kazakhstan
F. Lange
1Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Gertrudenstraße 9, 18057 Rostock, Germany
C. Johne
2Institute of Medical Biochemistry and Molecular Biology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany
S. Baltrusch
2Institute of Medical Biochemistry and Molecular Biology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany
M. Tiedge
2Institute of Medical Biochemistry and Molecular Biology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany
G. Fuellen
4Institute for Biostatistics and Informatics in Medicine and Ageing Research, Ernst-Heydemann-Str. 8, 18057 Rostock, Germany
5Interdisciplinary Faculty, University of Rostock, Germany
S. Ibrahim
3Department of Dermatology, Lübeck University Medical Center, Ratzeburger Allee, 23562 Lübeck, Germany
R. Köhling
1Oscar-Langendorff-Institute of Physiology, Rostock University Medical Center, Gertrudenstraße 9, 18057 Rostock, Germany
5Interdisciplinary Faculty, University of Rostock, Germany
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Posted December 13, 2017.
Combination of mitochondrial tRNA and OXPHOS mutation reduces lifespan and physical condition in aged mice
G. Reichart, J. Mayer, T. Tokay, F. Lange, C. Johne, S. Baltrusch, M. Tiedge, G. Fuellen, S. Ibrahim, R. Köhling
bioRxiv 233593; doi: https://doi.org/10.1101/233593
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