Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy

Martin Weigert; Uwe Schmidt; Tobias Boothe; Andreas Müller; Alexandr Dibrov; Akanksha Jain; Benjamin Wilhelm; Deborah Schmidt; Coleman Broaddus; Siân Culley; Mauricio Rocha-Martins; Fabián Segovia-Miranda; Caren Norden; Ricardo Henriques; Marino Zerial; Michele Solimena; Jochen Rink; Pavel Tomancak; Loic Royer; Florian Jug; Eugene W. Myers

doi:10.1101/236463

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Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy

doi: https://doi.org/10.1101/236463

Martin Weigert

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Uwe Schmidt

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Tobias Boothe

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Andreas Müller

8Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

9Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

10German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Alexandr Dibrov

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Akanksha Jain

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Benjamin Wilhelm

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

6University of Konstanz, Konstanz, Germany

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Deborah Schmidt

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

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Coleman Broaddus

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Siân Culley

4MRC Laboratory for Molecular Cell Biology, University College London, London, UK

5The Francis Crick Institute, London, UK

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Mauricio Rocha-Martins

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Fabián Segovia-Miranda

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Caren Norden

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Ricardo Henriques

4MRC Laboratory for Molecular Cell Biology, University College London, London, UK

5The Francis Crick Institute, London, UK

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Marino Zerial

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Michele Solimena

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

8Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

9Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

10German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Jochen Rink

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Pavel Tomancak

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Loic Royer

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

7CZ Biohub, San Francisco, USA

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Florian Jug

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

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Eugene W. Myers

1Center for Systems Biology Dresden (CSBD), Dresden, Germany

2Max-Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

3Department of Computer Science, Technical University Dresden

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Posted July 03, 2018.

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Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy

Martin Weigert, Uwe Schmidt, Tobias Boothe, Andreas Müller, Alexandr Dibrov, Akanksha Jain, Benjamin Wilhelm, Deborah Schmidt, Coleman Broaddus, Siân Culley, Mauricio Rocha-Martins, Fabián Segovia-Miranda, Caren Norden, Ricardo Henriques, Marino Zerial, Michele Solimena, Jochen Rink, Pavel Tomancak, Loic Royer, Florian Jug, Eugene W. Myers

bioRxiv 236463; doi: https://doi.org/10.1101/236463

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