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Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration

Rosemary C Challis, Sripriya Ravindra Kumar, Ken Y Chan, Collin Challis, Min J Jang, Pradeep S Rajendran, John D Tompkins, Kalyanam Shivkumar, Benjamin E Deverman, Viviana Gradinaru
doi: https://doi.org/10.1101/246405
Rosemary C Challis
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Sripriya Ravindra Kumar
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Ken Y Chan
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Collin Challis
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Min J Jang
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Pradeep S Rajendran
2Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles Los Angeles, CA
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John D Tompkins
2Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles Los Angeles, CA
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Kalyanam Shivkumar
2Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles Los Angeles, CA
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Benjamin E Deverman
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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Viviana Gradinaru
1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
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  • For correspondence: viviana@caltech.edu
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Article Information

doi 
https://doi.org/10.1101/246405
History 
  • January 19, 2018.

Article Versions

  • Version 1 (January 11, 2018 - 21:06).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Rosemary C Challis1,
  2. Sripriya Ravindra Kumar1,
  3. Ken Y Chan1,
  4. Collin Challis1,
  5. Min J Jang1,
  6. Pradeep S Rajendran2,
  7. John D Tompkins2,
  8. Kalyanam Shivkumar2,
  9. Benjamin E Deverman1 and
  10. Viviana Gradinaru1,*
  1. 1Division of Biology and Biological Engineering, California Institute of Technology Pasadena, CA
  2. 2Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles Los Angeles, CA
  1. ↵* To whom correspondence should be addressed: Viviana Gradinaru, Ph.D., Division of Biology and Biological Engineering, California Institute of Technology, 1200 East California Blvd. MC 156-29, Pasadena, CA 91125, Phone: (626) 395-6813, viviana{at}caltech.edu
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Posted January 19, 2018.
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Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration
Rosemary C Challis, Sripriya Ravindra Kumar, Ken Y Chan, Collin Challis, Min J Jang, Pradeep S Rajendran, John D Tompkins, Kalyanam Shivkumar, Benjamin E Deverman, Viviana Gradinaru
bioRxiv 246405; doi: https://doi.org/10.1101/246405
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Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration
Rosemary C Challis, Sripriya Ravindra Kumar, Ken Y Chan, Collin Challis, Min J Jang, Pradeep S Rajendran, John D Tompkins, Kalyanam Shivkumar, Benjamin E Deverman, Viviana Gradinaru
bioRxiv 246405; doi: https://doi.org/10.1101/246405

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