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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
View ORCID ProfileJonathan R.I. Coleman, Wouter J. Peyrot, View ORCID ProfileKirstin L. Purves, View ORCID ProfileKatrina A.S. Davis, Christopher Rayner, View ORCID ProfileShing Wan Choi, View ORCID ProfileChristopher Hübel, View ORCID ProfileHéléna A. Gaspar, View ORCID ProfileCarol Kan, View ORCID ProfileSandra Van der Auwera, View ORCID ProfileMark James Adams, View ORCID ProfileDonald M. Lyall, Karmel W. Choi, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, View ORCID ProfileErin C. Dunn, View ORCID ProfileEvangelos Vassos, View ORCID ProfileAndrea Danese, Barbara Maughan, View ORCID ProfileHans J. Grabe, View ORCID ProfileCathryn M. Lewis, View ORCID ProfilePaul F. O’Reilly, View ORCID ProfileAndrew M. McIntosh, View ORCID ProfileDaniel J. Smith, View ORCID ProfileNaomi R. Wray, View ORCID ProfileMatthew Hotopf, View ORCID ProfileThalia C. Eley, View ORCID ProfileGerome Breen
doi: https://doi.org/10.1101/247353
Jonathan R.I. Coleman
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Wouter J. Peyrot
3Amsterdam UMC, Vrije Universiteit Medical Center, Department of Psychiatry, Amsterdam, The Netherlands
Kirstin L. Purves
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Katrina A.S. Davis
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
4Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Christopher Rayner
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Shing Wan Choi
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Christopher Hübel
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Héléna A. Gaspar
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Carol Kan
4Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Sandra Van der Auwera
5Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Mark James Adams
6Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Donald M. Lyall
7Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
Karmel W. Choi
8Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
9Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA
10Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge, MA, USA
11Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
12Consortium members listed in Supplementary Materials
Erin C. Dunn
10Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Cambridge, MA, USA
11Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
13Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Evangelos Vassos
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Andrea Danese
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
14Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
15National and Specialist CAMHS Trauma and Anxiety Clinic, South London and Maudsley NHS Foundation Trust, London, UK
Barbara Maughan
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Hans J. Grabe
5Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Cathryn M. Lewis
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Paul F. O’Reilly
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Andrew M. McIntosh
6Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Daniel J. Smith
7Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
Naomi R. Wray
16Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia
17Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia
Matthew Hotopf
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
4Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Thalia C. Eley
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Gerome Breen
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
2NIHR Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, UK
Article usage
Posted May 13, 2019.
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Jonathan R.I. Coleman, Wouter J. Peyrot, Kirstin L. Purves, Katrina A.S. Davis, Christopher Rayner, Shing Wan Choi, Christopher Hübel, Héléna A. Gaspar, Carol Kan, Sandra Van der Auwera, Mark James Adams, Donald M. Lyall, Karmel W. Choi, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Erin C. Dunn, Evangelos Vassos, Andrea Danese, Barbara Maughan, Hans J. Grabe, Cathryn M. Lewis, Paul F. O’Reilly, Andrew M. McIntosh, Daniel J. Smith, Naomi R. Wray, Matthew Hotopf, Thalia C. Eley, Gerome Breen
bioRxiv 247353; doi: https://doi.org/10.1101/247353
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Jonathan R.I. Coleman, Wouter J. Peyrot, Kirstin L. Purves, Katrina A.S. Davis, Christopher Rayner, Shing Wan Choi, Christopher Hübel, Héléna A. Gaspar, Carol Kan, Sandra Van der Auwera, Mark James Adams, Donald M. Lyall, Karmel W. Choi, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Erin C. Dunn, Evangelos Vassos, Andrea Danese, Barbara Maughan, Hans J. Grabe, Cathryn M. Lewis, Paul F. O’Reilly, Andrew M. McIntosh, Daniel J. Smith, Naomi R. Wray, Matthew Hotopf, Thalia C. Eley, Gerome Breen
bioRxiv 247353; doi: https://doi.org/10.1101/247353
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