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Analysis of human immunoglobulin VDJ and DJ rearrangements shows N region synthesis by concatenation of cytosine-rich strands preferentially originating from trimmed germline gene segments

View ORCID ProfileTina Funck, View ORCID ProfileMike Bogetofte Barnkob, Nanna Holm, Line Ohm-Laursen, View ORCID ProfileCamilla Slot Mehlum, View ORCID ProfileSören Möller, View ORCID ProfileTorben Barington
doi: https://doi.org/10.1101/248021
Tina Funck
†Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
*Department of Clinical Biochemistry, Zealand University Hospital, Roskilde, Denmark.
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Mike Bogetofte Barnkob
†Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
‡Currently at MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxfordshire, UK.
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Nanna Holm
†Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
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Line Ohm-Laursen
§Randall Division of Cell & Molecular Biophysics, School of Basic and Medical Biosciences, King’s College London, London, UK.
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Camilla Slot Mehlum
¶Department of ORL – Head & Neck Surgery, Odense University Hospital, Odense, Denmark.
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Sören Möller
#OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark.
$Clinical Department, University of Southern Denmark, Odense, Denmark.
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Torben Barington
†Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
#OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark.
$Clinical Department, University of Southern Denmark, Odense, Denmark.
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Posted January 23, 2018.
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Analysis of human immunoglobulin VDJ and DJ rearrangements shows N region synthesis by concatenation of cytosine-rich strands preferentially originating from trimmed germline gene segments
Tina Funck, Mike Bogetofte Barnkob, Nanna Holm, Line Ohm-Laursen, Camilla Slot Mehlum, Sören Möller, Torben Barington
bioRxiv 248021; doi: https://doi.org/10.1101/248021
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Analysis of human immunoglobulin VDJ and DJ rearrangements shows N region synthesis by concatenation of cytosine-rich strands preferentially originating from trimmed germline gene segments
Tina Funck, Mike Bogetofte Barnkob, Nanna Holm, Line Ohm-Laursen, Camilla Slot Mehlum, Sören Möller, Torben Barington
bioRxiv 248021; doi: https://doi.org/10.1101/248021

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