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The Healthy Nevada Project: rapid recruitment for population health study

Joseph J Grzymski, Max J Coppes, Jim Metcalf, Christos Galanopoulos, Chris Rowan, Michele Henderson, Robert Read, Harry Reed, Bruce Lipp, Dave Miceli, Susan Rybarski, Anthony Slonim
doi: https://doi.org/10.1101/250274
Joseph J Grzymski
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
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  • For correspondence: joeg@dri.edu aslonim@renown.org
Max J Coppes
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
3Renown Health 50. W Liberty St Reno, NV 89501
4University of Nevada Reno School of Medicine 1664 N Virginia Street Reno, NV, 89557
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Jim Metcalf
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
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Christos Galanopoulos
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
3Renown Health 50. W Liberty St Reno, NV 89501
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Chris Rowan
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
3Renown Health 50. W Liberty St Reno, NV 89501
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Michele Henderson
2Renown Institute of Health Innovation 2215 Raggio Parkway Reno, NV 89512
3Renown Health 50. W Liberty St Reno, NV 89501
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Robert Read
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
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Harry Reed
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
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Bruce Lipp
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
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Dave Miceli
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
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Susan Rybarski
1Desert Research Institute Applied Innovation Center 2215 Raggio Parkway Reno, NV 89512
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Anthony Slonim
3Renown Health 50. W Liberty St Reno, NV 89501
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  • For correspondence: joeg@dri.edu aslonim@renown.org
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Abstract

Background Nevada ranks in the bottom half of overall health rankings in the United States. The majority of residents of Northern Nevada live in Washoe County, which is confounded with high age-adjusted death rates for heart disease, cancer and chronic lower respiratory disease.

Methods Saliva as a source of DNA was collected from adults in Northern Nevada as the first phase of a much larger (100,000 participants) effort to contribute to comprehensive population health studies in Nevada. The personal genetics company 23andMe was used to genotype the first 10,250 participants and deliver their custom ancestry, traits, wellness, and carrier status reports.

Results The study was announced by Governor Brian Sandoval on September 15, 2016 and within two days the registration of 9,700 volunteers for an appointment was complete. Processing of 9,344 participants was achieved in 3 months, with a no-show rate of just over 11%. The participant population was skewed to female and was less racially diverse than the population.

Conclusion DNA genotyping was administered free-of-charge and the patient population was representative of the socio-economic diversity in northern Nevada – indicating that free genetic testing is of interest to a broad swath of the population and a powerful motivator for comprehensive population health study research.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted January 19, 2018.
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The Healthy Nevada Project: rapid recruitment for population health study
Joseph J Grzymski, Max J Coppes, Jim Metcalf, Christos Galanopoulos, Chris Rowan, Michele Henderson, Robert Read, Harry Reed, Bruce Lipp, Dave Miceli, Susan Rybarski, Anthony Slonim
bioRxiv 250274; doi: https://doi.org/10.1101/250274
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The Healthy Nevada Project: rapid recruitment for population health study
Joseph J Grzymski, Max J Coppes, Jim Metcalf, Christos Galanopoulos, Chris Rowan, Michele Henderson, Robert Read, Harry Reed, Bruce Lipp, Dave Miceli, Susan Rybarski, Anthony Slonim
bioRxiv 250274; doi: https://doi.org/10.1101/250274

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