Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide

Maria Zhivagui; Maude Ardin; Alvin W.T. Ng; Mona I. Churchwell; Manuraj Pandey; Stephanie Villar; Vincent Cahais; Alexis Robitaille; Liacine Bouaoun; Adriana Heguy; Kathryn Guyton; Martha R. Stampfer; James McKay; Monica Hollstein; Magali Olivier; Steven G. Rozen; Frederick A. Beland; Michael Korenjak; Jiri Zavadil

doi:10.1101/254664

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Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide

Maria Zhivagui, Maude Ardin, Alvin W.T. Ng, Mona I. Churchwell, Manuraj Pandey, Stephanie Villar, Vincent Cahais, Alexis Robitaille, Liacine Bouaoun, Adriana Heguy, Kathryn Guyton, Martha R. Stampfer, James McKay, Monica Hollstein, Magali Olivier, Steven G. Rozen, Frederick A. Beland, Michael Korenjak, Jiri Zavadil

doi: https://doi.org/10.1101/254664

Maria Zhivagui

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Maude Ardin

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Alvin W.T. Ng

2Centre for Computational Biology, Duke-NUS Medical School, Singapore 169857, Singapore

3Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857, Singapore

4NUS Graduate School for Integrative Sciences and Engineering, 117456, Singapore

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Mona I. Churchwell

5Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA

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Manuraj Pandey

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Stephanie Villar

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Vincent Cahais

6Epigenetics Group, International Agency for Research on Cancer, Lyon 69008, France

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Alexis Robitaille

7Infections and Cancer Biology Group, International Agency for Research on Cancer, Lyon 69008, France

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Liacine Bouaoun

8Environment and Radiation Section, International Agency for Research on Cancer, Lyon 69008, France

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Adriana Heguy

9Department of Pathology and Genome Technology Center, New York University, Langone Medical Center, New York, NY 10016, USA

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Kathryn Guyton

10IARC Monographs Section, International Agency for Research on Cancer, Lyon 69008, France

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Martha R. Stampfer

11Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA

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James McKay

12Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon 69008, France

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Monica Hollstein

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

13Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany

14Faculty of Medicine and Health, University of Leeds, LIGHT Laboratories, Leeds LS2 9JT, United Kingdom

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Magali Olivier

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Steven G. Rozen

2Centre for Computational Biology, Duke-NUS Medical School, Singapore 169857, Singapore

3Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, 169857, Singapore

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Frederick A. Beland

5Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA

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Michael Korenjak

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Jiri Zavadil

1Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, Lyon 69008, France

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Posted January 27, 2018.

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Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide

bioRxiv 254664; doi: https://doi.org/10.1101/254664

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Experimental analysis of exome-scale mutational signature of glycidamide, the reactive metabolite of acrylamide

bioRxiv 254664; doi: https://doi.org/10.1101/254664

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