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A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling
View ORCID ProfileSebastian Scheer, View ORCID ProfileSuzanne Ackloo, View ORCID ProfileTiago S. Medina, View ORCID ProfileMatthieu Schapira, Fengling Li, View ORCID ProfileJennifer A. Ward, View ORCID ProfileAndrew M. Lewis, Jeffrey P. Northrop, Paul L. Richardson, H. Ümit Kaniskan, Yudao Shen, Jing Liu, View ORCID ProfileDavid Smil, Minkui Luo, Jian Jin, View ORCID ProfileDalia Barsyte-Lovejoy, View ORCID ProfileKilian V. M. Huber, View ORCID ProfileDaniel D. De Carvalho, Masoud Vedadi, View ORCID ProfileColby Zaph, View ORCID ProfilePeter J. Brown, View ORCID ProfileCheryl H. Arrowsmith
doi: https://doi.org/10.1101/260638
Sebastian Scheer
1Infection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton VIC 3800, Australia.
Suzanne Ackloo
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
Tiago S. Medina
3Princess Margaret Cancer Centre, University Health Network, Toronto ON M5G 2M9, Canada.
Matthieu Schapira
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
4Department of Pharmacology and Toxicology, University of Toronto, Toronto ON M5S 1A8, Canada.
Fengling Li
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
Jennifer A. Ward
5Structural Genomics Consortium, University of Oxford, Oxford OX3 7DQ, United Kingdom.
6Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom.
Andrew M. Lewis
5Structural Genomics Consortium, University of Oxford, Oxford OX3 7DQ, United Kingdom.
6Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom.
Jeffrey P. Northrop
1Infection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton VIC 3800, Australia.
Paul L. Richardson
7AbbVie Inc., 1 North Waukegan Rd., North Chicago, IL 60064 USA
H. Ümit Kaniskan
8Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA
Yudao Shen
8Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA
Jing Liu
8Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA
David Smil
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
Minkui Luo
9Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065 USA
10Program of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10021 USA
Jian Jin
8Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA
Dalia Barsyte-Lovejoy
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
Kilian V. M. Huber
5Structural Genomics Consortium, University of Oxford, Oxford OX3 7DQ, United Kingdom.
6Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, United Kingdom.
Daniel D. De Carvalho
3Princess Margaret Cancer Centre, University Health Network, Toronto ON M5G 2M9, Canada.
11Department of Medical Biophysics, University of Toronto, Toronto ON M5G 1L7, Canada.
Masoud Vedadi
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
4Department of Pharmacology and Toxicology, University of Toronto, Toronto ON M5S 1A8, Canada.
Colby Zaph
1Infection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton VIC 3800, Australia.
Peter J. Brown
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
Cheryl H. Arrowsmith
2Structural Genomics Consortium, University of Toronto, Toronto ON M5G 1L7, Canada.
3Princess Margaret Cancer Centre, University Health Network, Toronto ON M5G 2M9, Canada.
11Department of Medical Biophysics, University of Toronto, Toronto ON M5G 1L7, Canada.
12Lead Contact
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Posted February 07, 2018.
A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling
Sebastian Scheer, Suzanne Ackloo, Tiago S. Medina, Matthieu Schapira, Fengling Li, Jennifer A. Ward, Andrew M. Lewis, Jeffrey P. Northrop, Paul L. Richardson, H. Ümit Kaniskan, Yudao Shen, Jing Liu, David Smil, Minkui Luo, Jian Jin, Dalia Barsyte-Lovejoy, Kilian V. M. Huber, Daniel D. De Carvalho, Masoud Vedadi, Colby Zaph, Peter J. Brown, Cheryl H. Arrowsmith
bioRxiv 260638; doi: https://doi.org/10.1101/260638
A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling
Sebastian Scheer, Suzanne Ackloo, Tiago S. Medina, Matthieu Schapira, Fengling Li, Jennifer A. Ward, Andrew M. Lewis, Jeffrey P. Northrop, Paul L. Richardson, H. Ümit Kaniskan, Yudao Shen, Jing Liu, David Smil, Minkui Luo, Jian Jin, Dalia Barsyte-Lovejoy, Kilian V. M. Huber, Daniel D. De Carvalho, Masoud Vedadi, Colby Zaph, Peter J. Brown, Cheryl H. Arrowsmith
bioRxiv 260638; doi: https://doi.org/10.1101/260638
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