VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding; Federico M. Giorgi; Amanda Donnelly; Amy E. Cullen; Sankari Nagarajan; Luke A Selth; Florian Markowetz

doi:10.1101/266908

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VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

View ORCID ProfileAndrew N. Holding, View ORCID ProfileFederico M. Giorgi, Amanda Donnelly, Amy E. Cullen, View ORCID ProfileSankari Nagarajan, View ORCID ProfileLuke A Selth, View ORCID ProfileFlorian Markowetz

doi: https://doi.org/10.1101/266908

Andrew N. Holding

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

2The Alan Turing Institute, 96 Euston Road, Kings Cross, London NW1 2DB

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For correspondence: andrew.holding@cruk.cam.ac.uk

Federico M. Giorgi

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

3Department of Pharmacy and Biotechnology, University of Bologna, Via Selmi 3, Bologna, Italy

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Amanda Donnelly

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

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Amy E. Cullen

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

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Sankari Nagarajan

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

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Luke A Selth

4Dame Roma Mitchell Cancer Research Laboratories and Freemasons Foundation Centre for Men’s Health, Adelaide Medical School, The University of Adelaide, SA, Australia

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Florian Markowetz

1CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE

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Posted April 21, 2019.

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VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding, Federico M. Giorgi, Amanda Donnelly, Amy E. Cullen, Sankari Nagarajan, Luke A Selth, Florian Markowetz

bioRxiv 266908; doi: https://doi.org/10.1101/266908

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VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding, Federico M. Giorgi, Amanda Donnelly, Amy E. Cullen, Sankari Nagarajan, Luke A Selth, Florian Markowetz

bioRxiv 266908; doi: https://doi.org/10.1101/266908

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