New Results
Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells
Josh Tycko, Luis A. Barrera, Nicholas Huston, Ari E. Friedland, Xuebing Wu, Jonathan S. Gootenberg, Omar O. Abudayyeh, Vic E. Myer, Christopher J. Wilson, Patrick D. Hsu
doi: https://doi.org/10.1101/269399
Josh Tycko
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Luis A. Barrera
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Nicholas Huston
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
3Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA
Ari E. Friedland
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Xuebing Wu
4Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
Jonathan S. Gootenberg
5Department of Systems Biology, Harvard, Cambridge, MA 02138, USA
Omar O. Abudayyeh
6Department of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Vic E. Myer
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Christopher J. Wilson
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Patrick D. Hsu
1Editas Medicine, 11 Hurley St., Cambridge, MA 02141, USA
Article usage
Posted February 22, 2018.
Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells
Josh Tycko, Luis A. Barrera, Nicholas Huston, Ari E. Friedland, Xuebing Wu, Jonathan S. Gootenberg, Omar O. Abudayyeh, Vic E. Myer, Christopher J. Wilson, Patrick D. Hsu
bioRxiv 269399; doi: https://doi.org/10.1101/269399
Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells
Josh Tycko, Luis A. Barrera, Nicholas Huston, Ari E. Friedland, Xuebing Wu, Jonathan S. Gootenberg, Omar O. Abudayyeh, Vic E. Myer, Christopher J. Wilson, Patrick D. Hsu
bioRxiv 269399; doi: https://doi.org/10.1101/269399
Subject Area
Subject Areas
- Biochemistry (12756)
- Bioengineering (9637)
- Bioinformatics (31173)
- Biophysics (16065)
- Cancer Biology (13138)
- Cell Biology (18791)
- Clinical Trials (138)
- Developmental Biology (10169)
- Ecology (15146)
- Epidemiology (2067)
- Evolutionary Biology (19361)
- Genetics (12849)
- Genomics (17740)
- Immunology (12865)
- Microbiology (30125)
- Molecular Biology (12567)
- Neuroscience (65635)
- Paleontology (485)
- Pathology (2032)
- Pharmacology and Toxicology (3505)
- Physiology (5431)
- Plant Biology (11257)
- Synthetic Biology (3109)
- Systems Biology (7751)
- Zoology (1754)