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FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
View ORCID ProfileClaus J. Scholz, View ORCID ProfilePaweł Biernat, View ORCID ProfileMatthias Becker, View ORCID ProfileKevin Baßler, View ORCID ProfilePatrick Günther, Jenny Balfer, View ORCID ProfileHenning Dickten, Lars Flöer, Kathrin Heikamp, View ORCID ProfilePhilipp Angerer, Mathias Heilig, Ralf Karle, View ORCID ProfileMeike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, View ORCID ProfileThomas Ulas, View ORCID ProfileFabian Theis, Stephan Huthmacher, View ORCID ProfileChristina Kratsch, View ORCID ProfileJoachim L. Schultze
doi: https://doi.org/10.1101/272476
Claus J. Scholz
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Paweł Biernat
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Matthias Becker
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Kevin Baßler
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Patrick Günther
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Jenny Balfer
2Comma Soft AG, 53229 Bonn, Germany
Henning Dickten
2Comma Soft AG, 53229 Bonn, Germany
Lars Flöer
2Comma Soft AG, 53229 Bonn, Germany
Kathrin Heikamp
2Comma Soft AG, 53229 Bonn, Germany
Philipp Angerer
2Comma Soft AG, 53229 Bonn, Germany
3Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Center Munich, 85764 Munich, Germany
Mathias Heilig
2Comma Soft AG, 53229 Bonn, Germany
Ralf Karle
2Comma Soft AG, 53229 Bonn, Germany
Meike Köhler
2Comma Soft AG, 53229 Bonn, Germany
Thomas Mazurkiewicz
2Comma Soft AG, 53229 Bonn, Germany
Martin Mönnighoff
2Comma Soft AG, 53229 Bonn, Germany
Christian Sauer
2Comma Soft AG, 53229 Bonn, Germany
Albrecht Schick
2Comma Soft AG, 53229 Bonn, Germany
Gerhard Schlemm
2Comma Soft AG, 53229 Bonn, Germany
Roland Weigelt
2Comma Soft AG, 53229 Bonn, Germany
Martin Winkler
2Comma Soft AG, 53229 Bonn, Germany
Thomas Ulas
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
Fabian Theis
3Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Center Munich, 85764 Munich, Germany
Stephan Huthmacher
2Comma Soft AG, 53229 Bonn, Germany
Christina Kratsch
2Comma Soft AG, 53229 Bonn, Germany
Joachim L. Schultze
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
4Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, 53175 Bonn, Germany

Abstract
Recent technological advances enable genomics of individual cells, the building blocks of all living organisms. Single cell data characteristics differ from those of bulk data, which led to a plethora of new analytical strategies. However, solutions are only useful for experts and currently, there are no widely accepted gold standards for single cell data analysis. To meet the requirements of analytical flexibility, ease of use and data security, we developed FASTGenomics (https://fastgenomics.org) as a powerful, efficient, versatile, robust, safe and intuitive analytical ecosystem for single-cell transcriptomics.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Posted March 22, 2018.
FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
Claus J. Scholz, Paweł Biernat, Matthias Becker, Kevin Baßler, Patrick Günther, Jenny Balfer, Henning Dickten, Lars Flöer, Kathrin Heikamp, Philipp Angerer, Mathias Heilig, Ralf Karle, Meike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, Thomas Ulas, Fabian Theis, Stephan Huthmacher, Christina Kratsch, Joachim L. Schultze
bioRxiv 272476; doi: https://doi.org/10.1101/272476
FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
Claus J. Scholz, Paweł Biernat, Matthias Becker, Kevin Baßler, Patrick Günther, Jenny Balfer, Henning Dickten, Lars Flöer, Kathrin Heikamp, Philipp Angerer, Mathias Heilig, Ralf Karle, Meike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, Thomas Ulas, Fabian Theis, Stephan Huthmacher, Christina Kratsch, Joachim L. Schultze
bioRxiv 272476; doi: https://doi.org/10.1101/272476
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