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FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data

View ORCID ProfileClaus J. Scholz, View ORCID ProfilePaweł Biernat, View ORCID ProfileMatthias Becker, View ORCID ProfileKevin Baßler, View ORCID ProfilePatrick Günther, Jenny Balfer, View ORCID ProfileHenning Dickten, Lars Flöer, Kathrin Heikamp, View ORCID ProfilePhilipp Angerer, Mathias Heilig, Ralf Karle, View ORCID ProfileMeike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, View ORCID ProfileThomas Ulas, View ORCID ProfileFabian Theis, Stephan Huthmacher, View ORCID ProfileChristina Kratsch, View ORCID ProfileJoachim L. Schultze
doi: https://doi.org/10.1101/272476
Claus J. Scholz
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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  • ORCID record for Claus J. Scholz
Paweł Biernat
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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  • ORCID record for Paweł Biernat
Matthias Becker
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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Kevin Baßler
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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  • ORCID record for Kevin Baßler
Patrick Günther
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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Jenny Balfer
2Comma Soft AG, 53229 Bonn, Germany
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Henning Dickten
2Comma Soft AG, 53229 Bonn, Germany
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Lars Flöer
2Comma Soft AG, 53229 Bonn, Germany
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Kathrin Heikamp
2Comma Soft AG, 53229 Bonn, Germany
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Philipp Angerer
2Comma Soft AG, 53229 Bonn, Germany
3Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Center Munich, 85764 Munich, Germany
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Mathias Heilig
2Comma Soft AG, 53229 Bonn, Germany
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Ralf Karle
2Comma Soft AG, 53229 Bonn, Germany
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Meike Köhler
2Comma Soft AG, 53229 Bonn, Germany
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Thomas Mazurkiewicz
2Comma Soft AG, 53229 Bonn, Germany
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Martin Mönnighoff
2Comma Soft AG, 53229 Bonn, Germany
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Christian Sauer
2Comma Soft AG, 53229 Bonn, Germany
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Albrecht Schick
2Comma Soft AG, 53229 Bonn, Germany
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Gerhard Schlemm
2Comma Soft AG, 53229 Bonn, Germany
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Roland Weigelt
2Comma Soft AG, 53229 Bonn, Germany
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Martin Winkler
2Comma Soft AG, 53229 Bonn, Germany
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Thomas Ulas
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
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Fabian Theis
3Institute of Computational Biology, German Research Center for Environmental Health, Helmholtz Center Munich, 85764 Munich, Germany
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Stephan Huthmacher
2Comma Soft AG, 53229 Bonn, Germany
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Christina Kratsch
2Comma Soft AG, 53229 Bonn, Germany
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  • For correspondence: j.schultze@uni-bonn.de christina.kratsch@comma-soft.com
Joachim L. Schultze
1Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany
4Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases and the University of Bonn, 53175 Bonn, Germany
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  • ORCID record for Joachim L. Schultze
  • For correspondence: j.schultze@uni-bonn.de christina.kratsch@comma-soft.com
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Abstract

Recent technological advances enable genomics of individual cells, the building blocks of all living organisms. Single cell data characteristics differ from those of bulk data, which led to a plethora of new analytical strategies. However, solutions are only useful for experts and currently, there are no widely accepted gold standards for single cell data analysis. To meet the requirements of analytical flexibility, ease of use and data security, we developed FASTGenomics (https://fastgenomics.org) as a powerful, efficient, versatile, robust, safe and intuitive analytical ecosystem for single-cell transcriptomics.

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Posted March 22, 2018.
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FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
Claus J. Scholz, Paweł Biernat, Matthias Becker, Kevin Baßler, Patrick Günther, Jenny Balfer, Henning Dickten, Lars Flöer, Kathrin Heikamp, Philipp Angerer, Mathias Heilig, Ralf Karle, Meike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, Thomas Ulas, Fabian Theis, Stephan Huthmacher, Christina Kratsch, Joachim L. Schultze
bioRxiv 272476; doi: https://doi.org/10.1101/272476
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FASTGenomics: An analytical ecosystem for single-cell RNA sequencing data
Claus J. Scholz, Paweł Biernat, Matthias Becker, Kevin Baßler, Patrick Günther, Jenny Balfer, Henning Dickten, Lars Flöer, Kathrin Heikamp, Philipp Angerer, Mathias Heilig, Ralf Karle, Meike Köhler, Thomas Mazurkiewicz, Martin Mönnighoff, Christian Sauer, Albrecht Schick, Gerhard Schlemm, Roland Weigelt, Martin Winkler, Thomas Ulas, Fabian Theis, Stephan Huthmacher, Christina Kratsch, Joachim L. Schultze
bioRxiv 272476; doi: https://doi.org/10.1101/272476

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