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GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
View ORCID ProfileHassan S Dashti, Samuel E Jones, Andrew R Wood, View ORCID ProfileJacqueline M Lane, Vincent T. van Hees, View ORCID ProfileHeming Wang, Jessica A Rhodes, Yanwei Song, Krunal Patel, View ORCID ProfileSimon G Anderson, Robin Beaumont, David A Bechtold, Jack Bowden, View ORCID ProfileBrian E Cade, View ORCID ProfileMarta Garaulet, View ORCID ProfileSimon D Kyle, View ORCID ProfileMax A Little, Andrew S Loudon, Annemarie I Luik, View ORCID ProfileFrank AJL Scheer, View ORCID ProfileKai Spiegelhalder, Jessica Tyrrell, View ORCID ProfileDaniel J Gottlieb, View ORCID ProfileHenning Tiemeier, View ORCID ProfileDavid W Ray, View ORCID ProfileShaun M Purcell, View ORCID ProfileTimothy M Frayling, Susan Redline, Deborah A Lawlor, View ORCID ProfileMartin K Rutter, Michael N Weedon, View ORCID ProfileRicha Saxena
doi: https://doi.org/10.1101/274977
Hassan S Dashti
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
2Broad Institute, Cambridge, MA, USA
Samuel E Jones
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
Andrew R Wood
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
Jacqueline M Lane
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
2Broad Institute, Cambridge, MA, USA
4Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Vincent T. van Hees
5Netherlands eScience Center, Amsterdam, The Netherlands
Heming Wang
2Broad Institute, Cambridge, MA, USA
6Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA
7Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
Jessica A Rhodes
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
2Broad Institute, Cambridge, MA, USA
Yanwei Song
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
8Northeastern University College of Science, 176 Mugar Life Sciences, 360 Huntington Avenue, Boston, MA 02015
Krunal Patel
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
8Northeastern University College of Science, 176 Mugar Life Sciences, 360 Huntington Avenue, Boston, MA 02015
Simon G Anderson
9Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK (SA)
Robin Beaumont
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
David A Bechtold
10Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
Jack Bowden
11MRC Integrative Epidemiology Unit at the University of Bristol, UK
12Population Health Sciences, Bristol Medical School, University of Bristol, UK
Brian E Cade
2Broad Institute, Cambridge, MA, USA
6Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA
7Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
Marta Garaulet
13Department of Physiology, University of Murcia, Murcia, Spain.
14IMIB-Arrixaca, Murcia, Spain.
Simon D Kyle
15Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
Max A Little
16Department of Mathematics, Aston University, Birmingham, UK
17Media Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
Andrew S Loudon
10Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
Annemarie I Luik
15Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
Frank AJL Scheer
2Broad Institute, Cambridge, MA, USA
7Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
18Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women’s Hospital
Kai Spiegelhalder
19Clinic for Psychiatry and Psychotherapy, Medical Centre - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Jessica Tyrrell
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
Daniel J Gottlieb
6Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA
7Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
20VA Boston Healthcare System, Boston, MA, USA
Henning Tiemeier
21Deprtment of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, MA, USA
22Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands
David W Ray
10Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
Shaun M Purcell
23Department of Psychiatry, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA, 02015
Timothy M Frayling
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
Susan Redline
24Departments of Medicine, Brigham and Women’s Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston
Deborah A Lawlor
11MRC Integrative Epidemiology Unit at the University of Bristol, UK
12Population Health Sciences, Bristol Medical School, University of Bristol, UK
Martin K Rutter
10Division of Endocrinology, Diabetes & Gastroenterology, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK
25Manchester Diabetes Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
Michael N Weedon
3Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom
Richa Saxena
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
2Broad Institute, Cambridge, MA, USA
4Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Article usage
Posted April 19, 2018.
GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
Hassan S Dashti, Samuel E Jones, Andrew R Wood, Jacqueline M Lane, Vincent T. van Hees, Heming Wang, Jessica A Rhodes, Yanwei Song, Krunal Patel, Simon G Anderson, Robin Beaumont, David A Bechtold, Jack Bowden, Brian E Cade, Marta Garaulet, Simon D Kyle, Max A Little, Andrew S Loudon, Annemarie I Luik, Frank AJL Scheer, Kai Spiegelhalder, Jessica Tyrrell, Daniel J Gottlieb, Henning Tiemeier, David W Ray, Shaun M Purcell, Timothy M Frayling, Susan Redline, Deborah A Lawlor, Martin K Rutter, Michael N Weedon, Richa Saxena
bioRxiv 274977; doi: https://doi.org/10.1101/274977
GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
Hassan S Dashti, Samuel E Jones, Andrew R Wood, Jacqueline M Lane, Vincent T. van Hees, Heming Wang, Jessica A Rhodes, Yanwei Song, Krunal Patel, Simon G Anderson, Robin Beaumont, David A Bechtold, Jack Bowden, Brian E Cade, Marta Garaulet, Simon D Kyle, Max A Little, Andrew S Loudon, Annemarie I Luik, Frank AJL Scheer, Kai Spiegelhalder, Jessica Tyrrell, Daniel J Gottlieb, Henning Tiemeier, David W Ray, Shaun M Purcell, Timothy M Frayling, Susan Redline, Deborah A Lawlor, Martin K Rutter, Michael N Weedon, Richa Saxena
bioRxiv 274977; doi: https://doi.org/10.1101/274977
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