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A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies
Mohsen Afshar Bakooshli, Ethan S Lippmann, Ben Mulcahy, Kayee Tung, Elena Pegoraro, Henry Ahn, Howard Ginsberg, Mei Zhen, Randolph S Ashton, Penney M Gilbert
doi: https://doi.org/10.1101/275545
Mohsen Afshar Bakooshli
1Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada
2Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada
Ethan S Lippmann
3Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA
4Wisconsin Institute for Discovery, University of Wisconsin, Madison, WI, USA
5Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA
Ben Mulcahy
6Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
Kayee Tung
7Department of Surgery, University of Toronto, Toronto, ON, Canada
Elena Pegoraro
8Department of Neuroscience, University of Padova, Padova, Italy
Henry Ahn
7Department of Surgery, University of Toronto, Toronto, ON, Canada
Howard Ginsberg
1Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada
7Department of Surgery, University of Toronto, Toronto, ON, Canada
9Li Ka Shing Knowledge Institute, Saint Michael’s Hospital, Toronto, ON, Canada
Mei Zhen
6Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada
10Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
11Department of Physiology, University of Toronto, Toronto, ON, Canada
Randolph S Ashton
3Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA
4Wisconsin Institute for Discovery, University of Wisconsin, Madison, WI, USA
Penney M Gilbert
1Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada
2Donnelly Centre for Cellular and Biomolecular Research, Toronto, ON, Canada
12Department of Biochemistry, University of Toronto, Toronto, ON, Canada
Article usage
Posted March 02, 2018.
A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies
Mohsen Afshar Bakooshli, Ethan S Lippmann, Ben Mulcahy, Kayee Tung, Elena Pegoraro, Henry Ahn, Howard Ginsberg, Mei Zhen, Randolph S Ashton, Penney M Gilbert
bioRxiv 275545; doi: https://doi.org/10.1101/275545
A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies
Mohsen Afshar Bakooshli, Ethan S Lippmann, Ben Mulcahy, Kayee Tung, Elena Pegoraro, Henry Ahn, Howard Ginsberg, Mei Zhen, Randolph S Ashton, Penney M Gilbert
bioRxiv 275545; doi: https://doi.org/10.1101/275545
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