Optogenetic reconstitution reveals that Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

Masako Okumura; Toyoaki Natsume; Masato T. Kanemaki; Tomomi Kiyomitsu

doi:10.1101/277202

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Optogenetic reconstitution reveals that Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

Masako Okumura, Toyoaki Natsume, Masato T. Kanemaki, Tomomi Kiyomitsu

doi: https://doi.org/10.1101/277202

Masako Okumura

1Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan

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Toyoaki Natsume

3Division of Molecular Cell Engineering, National Institute of Genetics, Research Organization of Information and Systems, Yata 1111, Mishima, Shizuoka 411-8540, Japan

4Department of Genetics, SOKENDAI, Yata 1111, Mishima, Shizuoka 411-8540, Japan

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Masato T. Kanemaki

2Precursory Research for Embryonic Science and Technology (PRESTO) Program, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan

3Division of Molecular Cell Engineering, National Institute of Genetics, Research Organization of Information and Systems, Yata 1111, Mishima, Shizuoka 411-8540, Japan

4Department of Genetics, SOKENDAI, Yata 1111, Mishima, Shizuoka 411-8540, Japan

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Tomomi Kiyomitsu

1Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan

2Precursory Research for Embryonic Science and Technology (PRESTO) Program, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan