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Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces
David Bowkett, Romain Talon, Cynthia Tallant, Chris Schofield, Frank von Delft, Stefan Knapp, Gordon Bruton, Paul E. Brennan
doi: https://doi.org/10.1101/283069
David Bowkett
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
Romain Talon
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
Cynthia Tallant
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
Chris Schofield
bChemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA (UK)
Frank von Delft
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
cDiamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE (UK)
dDepartment of Biochemistry, University of Johannesburg, Auckland Park 2006 (South Africa)
Stefan Knapp
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
eInstitute for Pharmaceutical Chemistry and Buchmann Institute for Life Sciences, Johann Wolfgang Goethe-University, Frankfurt am Main 60438 (Germany)
Gordon Bruton
fGlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY (UK)
Paul E. Brennan
aStructural Genomics Consortium & Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
gAlzheimer’s Research UK Oxford Drug Discovery Institute, Nuffield Department of Medicine, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford OX3 7FZ (UK)
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Posted March 16, 2018.
Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces
David Bowkett, Romain Talon, Cynthia Tallant, Chris Schofield, Frank von Delft, Stefan Knapp, Gordon Bruton, Paul E. Brennan
bioRxiv 283069; doi: https://doi.org/10.1101/283069
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