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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
doi: https://doi.org/10.1101/283440
Jing-Xiang Wu
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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Dian Ding
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Mengmeng Wang
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Yunlu Kang
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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Xin Zeng
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Lei Chen
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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  • For correspondence: chenlei2016@pku.edu.cn
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Article Information

doi 
https://doi.org/10.1101/283440
History 
  • March 16, 2018.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jing-Xiang Wu1,2,
  2. Dian Ding1,2,3,
  3. Mengmeng Wang1,2,3,
  4. Yunlu Kang1,2,
  5. Xin Zeng1,2,3 and
  6. Lei Chen1,2,*
  1. 1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
  2. 2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
  3. 3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
  1. ↵*Correspondence:
    Lei Chen, chenlei2016{at}pku.edu.cn
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Posted March 16, 2018.
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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels
Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
bioRxiv 283440; doi: https://doi.org/10.1101/283440
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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels
Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
bioRxiv 283440; doi: https://doi.org/10.1101/283440

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