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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
doi: https://doi.org/10.1101/283440
Jing-Xiang Wu
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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Dian Ding
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Mengmeng Wang
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Yunlu Kang
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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Xin Zeng
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
3Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
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Lei Chen
1State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing 100871, China
2Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
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  • For correspondence: chenlei2016@pku.edu.cn
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Posted March 16, 2018.
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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels
Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
bioRxiv 283440; doi: https://doi.org/10.1101/283440
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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels
Jing-Xiang Wu, Dian Ding, Mengmeng Wang, Yunlu Kang, Xin Zeng, Lei Chen
bioRxiv 283440; doi: https://doi.org/10.1101/283440

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