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A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
View ORCID ProfileDwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, View ORCID ProfileMadeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
doi: https://doi.org/10.1101/286500
Dwi U. Kemaladewi
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Prabhpreet S. Bassi
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
Steven Erwood
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
Dhekra Al-Basha
3Program in Neuroscience and Mental Health, the Hospital for Sick Children Research Institute, Toronto, Canada
4Department of Physiology, University of Toronto, Canada
Kinga I. Gawlik
5Unit of Muscle Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden
Kyle Lindsay
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Ella Hyatt
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Rebekah Kember
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Kara M. Place
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Ryan M. Marks
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Madeleine Durbeej
5Unit of Muscle Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden
Steven A. Prescott
3Program in Neuroscience and Mental Health, the Hospital for Sick Children Research Institute, Toronto, Canada
4Department of Physiology, University of Toronto, Canada
6Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
Evgueni A. Ivakine
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
Ronald D. Cohn
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
7Department of Pediatrics, the Hospital for Sick Children, Toronto, Canada


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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Posted November 11, 2018.
A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
bioRxiv 286500; doi: https://doi.org/10.1101/286500
A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
bioRxiv 286500; doi: https://doi.org/10.1101/286500
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