Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo

View ORCID ProfileDwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, View ORCID ProfileMadeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
doi: https://doi.org/10.1101/286500
Dwi U. Kemaladewi
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Dwi U. Kemaladewi
Prabhpreet S. Bassi
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Steven Erwood
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dhekra Al-Basha
3Program in Neuroscience and Mental Health, the Hospital for Sick Children Research Institute, Toronto, Canada
4Department of Physiology, University of Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kinga I. Gawlik
5Unit of Muscle Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kyle Lindsay
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ella Hyatt
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rebekah Kember
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kara M. Place
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ryan M. Marks
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Madeleine Durbeej
5Unit of Muscle Biology, Department of Experimental Medical Science, Lund University, Lund, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Madeleine Durbeej
Steven A. Prescott
3Program in Neuroscience and Mental Health, the Hospital for Sick Children Research Institute, Toronto, Canada
4Department of Physiology, University of Toronto, Canada
6Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Evgueni A. Ivakine
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ronald D. Cohn
1Program in Genetics and Genome Biology, the Hospital for Sick Children Research Institute, Toronto, Canada
2Department of Molecular Genetics, University of Toronto, Canada
7Department of Pediatrics, the Hospital for Sick Children, Toronto, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading
PDF extract preview

You do not have access to the full text of this article, the first page of the PDF of this article appears above.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted November 11, 2018.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
bioRxiv 286500; doi: https://doi.org/10.1101/286500
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
A mutation-independent approach via transcriptional upregulation of a disease modifier gene rescues muscular dystrophy in vivo
Dwi U. Kemaladewi, Prabhpreet S. Bassi, Steven Erwood, Dhekra Al-Basha, Kinga I. Gawlik, Kyle Lindsay, Ella Hyatt, Rebekah Kember, Kara M. Place, Ryan M. Marks, Madeleine Durbeej, Steven A. Prescott, Evgueni A. Ivakine, Ronald D. Cohn
bioRxiv 286500; doi: https://doi.org/10.1101/286500

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genetics
Subject Areas
All Articles
  • Animal Behavior and Cognition (3609)
  • Biochemistry (7585)
  • Bioengineering (5533)
  • Bioinformatics (20820)
  • Biophysics (10343)
  • Cancer Biology (7995)
  • Cell Biology (11653)
  • Clinical Trials (138)
  • Developmental Biology (6616)
  • Ecology (10222)
  • Epidemiology (2065)
  • Evolutionary Biology (13639)
  • Genetics (9553)
  • Genomics (12856)
  • Immunology (7929)
  • Microbiology (19561)
  • Molecular Biology (7675)
  • Neuroscience (42174)
  • Paleontology (308)
  • Pathology (1259)
  • Pharmacology and Toxicology (2206)
  • Physiology (3271)
  • Plant Biology (7054)
  • Scientific Communication and Education (1295)
  • Synthetic Biology (1953)
  • Systems Biology (5433)
  • Zoology (1119)