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MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
Jennifer Hüllein, Mikołaj Słabicki, Maciej Rosolowski, Alexander Jethwa, Stefan Habringer, Katarzyna Tomska, Roma Kurilov, Junyan Lu, Sebastian Scheinost, Rabea Wagener, Zhiqin Huang, Marina Lukas, Olena Yavorska, Hanne Helferich, René Scholtysik, Kyle Bonneau, Donato Tedesco, Ralf Küppers, Wolfram Klapper, Christiane Pott, Stephan Stilgenbauer, Birgit Burkhardt, Markus Löffler, Lorenz Trümper, Michael Hummel, Benedikt Brors, Marc Zapatka, Reiner Siebert, consortium MMML, Ulrich Keller, Wolfgang Huber, Markus Kreuz, Thorsten Zenz
doi: https://doi.org/10.1101/289363
Jennifer Hüllein
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
2Faculty of Biosciences, Heidelberg University, Heidelberg, Germany
Mikołaj Słabicki
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
Maciej Rosolowski
3Department for Statistics and Epidemiology, Institute for Medical Informatics, Leipzig, Germany
Alexander Jethwa
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
2Faculty of Biosciences, Heidelberg University, Heidelberg, Germany
Stefan Habringer
4III. Medical Department of Hematology and Medical Oncology, Technical University of Munich, Germany
Katarzyna Tomska
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
Roma Kurilov
5Division of Applied Bioinformatics, DKFZ, Heidelberg, Germany
Junyan Lu
6European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
Sebastian Scheinost
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
Rabea Wagener
7Institute of Human Genetics, Ulm University & Ulm University Medical Center, Germany
8Institute of Human Genetics, University of Kiel, Kiel, Germany
Zhiqin Huang
9Division of Molecular Genetics, DKFZ, Heidelberg, Germany
Marina Lukas
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
Olena Yavorska
6European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
Hanne Helferich
10Department of Internal Medicine III, University of Ulm, Germany
René Scholtysik
11Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Medical School, Essen, Germany
Kyle Bonneau
12Cellecta, Inc., Mountain View, CA 94043
Donato Tedesco
12Cellecta, Inc., Mountain View, CA 94043
Ralf Küppers
11Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Medical School, Essen, Germany
Wolfram Klapper
13Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel, Christian-Albrechts-University Kiel, Kiel, Germany
Christiane Pott
14Second Medical Department, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
Stephan Stilgenbauer
10Department of Internal Medicine III, University of Ulm, Germany
Birgit Burkhardt
15Department of Pediatric Hematology and Oncology, NHL-BFM Study Center, University Children’s Hospital, Münster, Germany
Markus Löffler
3Department for Statistics and Epidemiology, Institute for Medical Informatics, Leipzig, Germany
Lorenz Trümper
16Department of Hematology and Medical Oncology, Göttingen University Medical Center, Göttingen, Germany
Michael Hummel
17Institute of Pathology, Charité–University Medicine Berlin, Berlin, Germany
Benedikt Brors
5Division of Applied Bioinformatics, DKFZ, Heidelberg, Germany
Marc Zapatka
9Division of Molecular Genetics, DKFZ, Heidelberg, Germany
Reiner Siebert
7Institute of Human Genetics, Ulm University & Ulm University Medical Center, Germany
8Institute of Human Genetics, University of Kiel, Kiel, Germany
Ulrich Keller
4III. Medical Department of Hematology and Medical Oncology, Technical University of Munich, Germany
Wolfgang Huber
6European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
Markus Kreuz
3Department for Statistics and Epidemiology, Institute for Medical Informatics, Leipzig, Germany
Thorsten Zenz
1Molecular Therapy in Hematology and Oncology & Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany
18Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
19Department of Hematology, University Hospital Zurich, Zurich, Switzerland
Article usage
Posted April 09, 2018.
MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
Jennifer Hüllein, Mikołaj Słabicki, Maciej Rosolowski, Alexander Jethwa, Stefan Habringer, Katarzyna Tomska, Roma Kurilov, Junyan Lu, Sebastian Scheinost, Rabea Wagener, Zhiqin Huang, Marina Lukas, Olena Yavorska, Hanne Helferich, René Scholtysik, Kyle Bonneau, Donato Tedesco, Ralf Küppers, Wolfram Klapper, Christiane Pott, Stephan Stilgenbauer, Birgit Burkhardt, Markus Löffler, Lorenz Trümper, Michael Hummel, Benedikt Brors, Marc Zapatka, Reiner Siebert, consortium MMML, Ulrich Keller, Wolfgang Huber, Markus Kreuz, Thorsten Zenz
bioRxiv 289363; doi: https://doi.org/10.1101/289363
MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
Jennifer Hüllein, Mikołaj Słabicki, Maciej Rosolowski, Alexander Jethwa, Stefan Habringer, Katarzyna Tomska, Roma Kurilov, Junyan Lu, Sebastian Scheinost, Rabea Wagener, Zhiqin Huang, Marina Lukas, Olena Yavorska, Hanne Helferich, René Scholtysik, Kyle Bonneau, Donato Tedesco, Ralf Küppers, Wolfram Klapper, Christiane Pott, Stephan Stilgenbauer, Birgit Burkhardt, Markus Löffler, Lorenz Trümper, Michael Hummel, Benedikt Brors, Marc Zapatka, Reiner Siebert, consortium MMML, Ulrich Keller, Wolfgang Huber, Markus Kreuz, Thorsten Zenz
bioRxiv 289363; doi: https://doi.org/10.1101/289363
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