Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Mukesh Bansal; Jing He; Michael Peyton; Manjunath Kaustagi; Archana Iyer; Michael Comb; Michael White; John Minna; Andrea Califano

doi:10.1101/289603

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Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Mukesh Bansal, Jing He, Michael Peyton, Manjunath Kaustagi, Archana Iyer, Michael Comb, Michael White, John Minna, Andrea Califano

doi: https://doi.org/10.1101/289603

Mukesh Bansal

1Psychogenics Inc. Tarrytown, New York, USA

2Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York

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For correspondence: mukesh.bansal@psychogenics.com ac2248@cumc.columbia.edu

Jing He

3Department of Systems Biology, Columbia University, New York, NY

4Center for Computational Biology and Bioinformatics (C2B2), Columbia University, New York, NY, USA

5Department of Biomedical Informatics (DBMI), Columbia University, New York, NY, USA

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Michael Peyton

6Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA

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Manjunath Kaustagi

3Department of Systems Biology, Columbia University, New York, NY

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Archana Iyer

3Department of Systems Biology, Columbia University, New York, NY

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Michael Comb

10Cell Signaling Technology, 3 Trask Lane, Danvers, MA 01923, USA

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Michael White

6Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA

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John Minna

11Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, Departments of Pharmacology, and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas

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Andrea Califano

3Department of Systems Biology, Columbia University, New York, NY

4Center for Computational Biology and Bioinformatics (C2B2), Columbia University, New York, NY, USA

5Department of Biomedical Informatics (DBMI), Columbia University, New York, NY, USA

7Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY

8Institute for Cancer Genetics, Columbia University, New York, NY

9Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY

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For correspondence: mukesh.bansal@psychogenics.com ac2248@cumc.columbia.edu

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Posted April 03, 2018.

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Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Mukesh Bansal, Jing He, Michael Peyton, Manjunath Kaustagi, Archana Iyer, Michael Comb, Michael White, John Minna, Andrea Califano

bioRxiv 289603; doi: https://doi.org/10.1101/289603

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Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Mukesh Bansal, Jing He, Michael Peyton, Manjunath Kaustagi, Archana Iyer, Michael Comb, Michael White, John Minna, Andrea Califano

bioRxiv 289603; doi: https://doi.org/10.1101/289603

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