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A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function
Lea M. Starita, Muhtadi M. Islam, Tapahsama Banerjee, Aleksandra I. Adamovich, Justin Gullingsrud, Stanley Fields, Jay Shendure, Jeffrey D. Parvin
doi: https://doi.org/10.1101/295279
Lea M. Starita
1Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
2Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.
7These authors contributed equally to this work.
Muhtadi M. Islam
3Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA.
7These authors contributed equally to this work.
Tapahsama Banerjee
3Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA.
Aleksandra I. Adamovich
3Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA.
Justin Gullingsrud
1Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
Stanley Fields
1Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
4Department of Medicine, University of Washington, Seattle, Washington, USA.
5Howard Hughes Medical Institute, Seattle, Washington, USA.
Jay Shendure
1Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
2Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.
5Howard Hughes Medical Institute, Seattle, Washington, USA.
Jeffrey D. Parvin
3Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA.
6The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.
Article usage
Posted April 05, 2018.
A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function
Lea M. Starita, Muhtadi M. Islam, Tapahsama Banerjee, Aleksandra I. Adamovich, Justin Gullingsrud, Stanley Fields, Jay Shendure, Jeffrey D. Parvin
bioRxiv 295279; doi: https://doi.org/10.1101/295279
A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function
Lea M. Starita, Muhtadi M. Islam, Tapahsama Banerjee, Aleksandra I. Adamovich, Justin Gullingsrud, Stanley Fields, Jay Shendure, Jeffrey D. Parvin
bioRxiv 295279; doi: https://doi.org/10.1101/295279
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