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MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy
Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel, Barbara McDonough, Dan Liao, Jianming Jiang, Angela Tai, Josh Gorham, Ida G. Lunde, Mingyue Lun, Thomas L. Lynch IV, Sakthivel Sadayappan, Charles S. Redwood, Hugh Watkins, View ORCID ProfileJonathan Seidman, Christine Seidman
doi: https://doi.org/10.1101/304204
Christopher N. Toepfer
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
2Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford
3Wellcome Centre for Human Genetics, University of Oxford.
Hiroko Wakimoto
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
4Cardiology, Children’s Hospital Boston, Boston, MA, USA.
Amanda C. Garfinkel
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
Barbara McDonough
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
Dan Liao
5Department of Biochemistry & Cardiovascular Research Institute(CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jianming Jiang
5Department of Biochemistry & Cardiovascular Research Institute(CVRI), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Angela Tai
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
Josh Gorham
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
Ida G. Lunde
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
6Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Mingyue Lun
7Department of Medicine, Division of Genetics, Brigham and Women’s Hospital, Boston, Massachusetts, USA.
Thomas L. Lynch IV
8Department of Molecular Pharmacology and Therapeutics, Health Sciences Division, Loyola University Chicago, Maywood, Illinois 60153
Sakthivel Sadayappan
9Division of Cardiovascular Health and Disease, Heart, Lung and Vascular Institute, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA
Charles S. Redwood
2Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford
Hugh Watkins
2Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford
3Wellcome Centre for Human Genetics, University of Oxford.
Jonathan Seidman
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
Christine Seidman
1Department of Genetics, Harvard Medical School, Boston, MA, USA.
10Howard Hughes Medical Institute, Brigham and Women’s Hospital, Boston, MA, USA
Posted April 18, 2018.
MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy
Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel, Barbara McDonough, Dan Liao, Jianming Jiang, Angela Tai, Josh Gorham, Ida G. Lunde, Mingyue Lun, Thomas L. Lynch IV, Sakthivel Sadayappan, Charles S. Redwood, Hugh Watkins, Jonathan Seidman, Christine Seidman
bioRxiv 304204; doi: https://doi.org/10.1101/304204
MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy
Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel, Barbara McDonough, Dan Liao, Jianming Jiang, Angela Tai, Josh Gorham, Ida G. Lunde, Mingyue Lun, Thomas L. Lynch IV, Sakthivel Sadayappan, Charles S. Redwood, Hugh Watkins, Jonathan Seidman, Christine Seidman
bioRxiv 304204; doi: https://doi.org/10.1101/304204
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