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- April 25, 2018.
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- Sali M.K. Farhan1,2,3,23,*,
- Daniel P. Howrigan1,2,3,
- Liam E. Abbott1,2,
- Andrea E. Byrnes1,2,3,
- Claire Churchhouse1,2,3,
- Hemali Phatnani4,
- Bradley N. Smith5,
- Simon D. Topp5,
- Evadnie Rampersaud6,
- Gang Wu6,
- Joanne Wuu7,
- Amelie Gubitz8,
- Joseph R. Klim9,
- Daniel A. Mordes9,
- Sulagna Ghosh3,9,
- CReATe Consortium, FALS Consortium, ALSGENS Consortium,
- Kevin Eggan3,9,
- Rosa Rademakers10,
- Jacob L. McCauley11,12,
- Rebecca Schüle13,
- Stephan Züchner11,12,
- Michael Benatar7,
- J. Paul Taylor14,15,
- Mike A. Nalls16,17,
- Bryan Traynor18,19,
- Christopher E. Shaw5,20,
- David B. Goldstein21,
- Matthew B. Harms22,
- Mark J. Daly1,2,3 and
- Benjamin M. Neale1,2,3,*
- 1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
- 2Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA 02142, USA.
- 3Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
- 4Center for Genomics of Neurodegenerative Disease, New York Genome Center, New York, NY 10013, USA.
- 5United Kingdom Dementia Research Institute Centre, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 9NU, U.K.
- 6Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA.
- 7Department of Neurology, University of Miami, Miami, FL 33136, USA.
- 8National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20824, USA.
- 9Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.
- 10Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
- 11John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
- 12The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
- 13Center for Neurology and Hertie Institute für Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany. German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.
- 14Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
- 15Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA.
- 16Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA.
- 17Data Tecnica International, Glen Echo, MD 20812, USA.
- 18Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging, NIH, Porter Neuroscience Research Center, Bethesda, MD 20892, USA.
- 19Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
- 20Centre for Brain Research, University of Auckland, Auckland, New Zealand.
- 21Institute for Genomic Medicine, Columbia University, New York, NY 10032, USA.
- 22Department of Neurology, Columbia University, New York, NY 10032, USA.
- ↵*Correspondence: sfarhan{at}broadinstitute.org (S.M.K.F.), bneale{at}broadinstitute.org (B.M.N.)