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Numeric Analysis of Temperature Distribution in Man using a 3D Human Model

Sipho Mfolozi, Arnaud Malan, Tunde Bello-Ochende, Lorna J. Martin
doi: https://doi.org/10.1101/330357
Sipho Mfolozi
aDepartment of Forensic Medicine, University of KwaZulu-Natal, Durban, KwaZulu-Natal Province, South Africa
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  • For correspondence: MfoloziS@ukzn.ac.za
Arnaud Malan
bDepartment of Mechanical Engineering, University of Cape Town, Cape Town, Western Cape Province, South Africa
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Tunde Bello-Ochende
bDepartment of Mechanical Engineering, University of Cape Town, Cape Town, Western Cape Province, South Africa
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Lorna J. Martin
cDivision of Forensic Medicine, University of Cape Town, Cape Town, Western Cape Province, South Africa
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Abstract

Premortem three-dimensional body temperature is the basis on which post-mortem cooling commences. Thermo-numeric analysis of post-mortem cooling for death-time calculation applies pre-mortem three-dimensional body temperature as initial conditions; therefore, an accurate determination of this distribution is important. To date, such prediction is not performed. This paper presents a thermo-numeric analysis method of predicting premortem three-dimensional body temperature in man, to be applied in thermo-numeric analysis of the post-mortem interval using the finite-difference time-domain method. The method applied a Pennes BioHeat Equation modified to linearize organ metabolic and blood flow rates with temperature in a transient thermo-numeric analysis scheme to predict naked three-dimensional temperatures of an MRI-built, 3D human model having 247 segmented organs and 58 categories of material properties under chosen boundary conditions. Organ metabolic heat and blood perfusion rates appropriate for a chosen pre-mortem physical activity, and known organ physical and thermal properties, were assigned to each organ. A steady-state temperature equilibration occurred after 8400 seconds. Predicted organ temperatures were topographically inhomogeneous. Skin temperatures varied between 20.5°C and 42.5°C, liver capsule temperatures were lower than parenchymal, and rectal luminal temperature were uniform.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
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Posted May 24, 2018.
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Numeric Analysis of Temperature Distribution in Man using a 3D Human Model
Sipho Mfolozi, Arnaud Malan, Tunde Bello-Ochende, Lorna J. Martin
bioRxiv 330357; doi: https://doi.org/10.1101/330357
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Numeric Analysis of Temperature Distribution in Man using a 3D Human Model
Sipho Mfolozi, Arnaud Malan, Tunde Bello-Ochende, Lorna J. Martin
bioRxiv 330357; doi: https://doi.org/10.1101/330357

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